23181

Chloromethyl chloroformate

≥98.0% (GC)

• 동의어(들): 1-Chloromethyl chloroformate, Chloroformic acid chloromethyl ester, Chloromethoxycarbonyl chloride, Chloromethyl carbonochloridate, Chloromethyl chlorocarbonate
• Linear Formula: ClCOOCH₂Cl
• CAS Number: 22128-62-7
• Molecular Weight: 128.94
• Beilstein: 506426
• EC Number: 244-793-3
• MDL number: MFCD00077688
• UNSPSC 코드: 12352100
• PubChem Substance ID: 57648023
• NACRES: NA.22

속성

• Quality Level: 200
• 분석: ≥98.0% (GC)
• 양식: liquid
• refractive index: n20/D 1.428
• bp: 107-108 °C (lit.)
• density: 1.450 g/mL at 20 °C
• 작용기: chloro
• 저장 온도: 2-8°C
• SMILES string: ClCOC(Cl)=O
• InChI: 1S/C2H2Cl2O2/c3-1-6-2(4)5/h1H2
• InChI key: JYWJULGYGOLCGW-UHFFFAOYSA-N

설명

애플리케이션

Chloromethyl chloroformate was used as key reactant in the synthesis of:

• novel aminocarbonyloxymethyl esters of diclofenac and flufenamic acid
• highly water-soluble monomethoxypoly(ethyleneglycol) prodrugs of cyclosporin A
• series of 3-acyloxymethyloxycarbonyl-1-aryl-3-methyltriazenes

안전성 정보

• 픽토그램: GHS06,GHS05
• 신호어: Danger
• 유해 및 위험 성명서: H314,H331
• 예방조치 성명서: P261 - P271 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Inhalation - Skin Corr. 1B
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point (°F): 203.0 °F - closed cup
• Flash Point (°C): 95 °C - closed cup
• 개인 보호 장비: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter