248193

3′-Chloropropiophenone

98%

• Linear Formula: ClC₆H₄COC₂H₅
• CAS Number: 34841-35-5
• Molecular Weight: 168.62
• EC Number: 252-242-3
• MDL number: MFCD00009925
• UNSPSC 코드: 12352100
• PubChem Substance ID: 24854919
• NACRES: NA.22

속성

• Quality Level: 100
• 분석: 98%
• 양식: solid
• bp: 124 °C/14 mmHg (lit.)
• mp: 45-47 °C (lit.)
• 작용기: chloro; ketone
• SMILES string: CCC(=O)c1cccc(Cl)c1
• InChI: 1S/C9H9ClO/c1-2-9(11)7-4-3-5-8(10)6-7/h3-6H,2H2,1H3
• InChI key: PQWGFUFROKIJBO-UHFFFAOYSA-N

설명

일반 설명

Influence of solvents and temperature on the yield and enantioselectivity of the phenylation of 3′-chloropropiophenone has been investigated.

애플리케이션

3′-Chloropropiophenone can be used as a reactant to synthesize:

• (S)-3-chloro-1-phenylpropanol via bio-catalyzed asymmetric reduction method.
• 1-(3-Chlorophenyl)-1-phenyl-1-propanol by phenylation with diphenylzinc in the presence of dihydroxy bis(sulfonamide) ligand.
• (S)-Dapoxetine, a selective serotonin reuptake inhibitor.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)