330752
Triphosgene
reagent grade, 98%
동의어(들):
Bis(trichloromethyl) carbonate
로그인조직 및 계약 가격 보기
크기 선택
크기 선택
보기 변경
About This Item
Linear Formula:
Cl3COCOOCCl3
CAS Number:
Molecular Weight:
296.75
Beilstein:
1787583
EC Number:
MDL number:
UNSPSC 코드:
12352108
PubChem Substance ID:
NACRES:
NA.22
일반 설명
Triphosgene [Bis(trichloromethyl)carbonate] is a versatile organic reagent used in organic synthesis alternative to phosgene. A catalytic amount of triphosgene is particularly used in chloroformylations, carbonylations, chlorinations, and dehydration reactions.
It is also commonly employed as a coupling agent in the synthesis of carbonyl compounds.
It is also commonly employed as a coupling agent in the synthesis of carbonyl compounds.
애플리케이션
Triphosgene can be employed as a reagent to prepare:
- Thiocarbonates from thiols and alcohols by one-pot, three-component reaction.
- Substituted azetidin-2-ones from acids and imines via ketene–imine cycloaddition reaction.
- Methyl (S)-2-isocyanato-3-phenylpropanoate from L-phenylalanine methyl ester hydrochloride in the presence of sodium bicarbonate.
- Acyl azides derivatives from various carboxylic acids and sodium azide.
- Immunosuppressant agent cyclosporin by solid-phase peptide synthesis.
- Allyl azides from allyl alcohols and sodium azide in one pot method.
- Esterification coupling reagent di-2-thienyl carbonate, from 2(5H)-thiophenone.
- 2-Chloronicotinaldehydes via cyclization of the corresponding enamides.
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 1 Inhalation - Skin Corr. 1B
Storage Class Code
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.