345571

1,5,7-Triazabicyclo[4.4.0]dec-5-ene

98%

• 동의어(들): 1,3,4,6,7,8-Hexahydro-2H-pyrimido[1,2-a]pyrimidine, Hhpp, TBD
• 실험식(Hill 표기법): C₇H₁₃N₃
• CAS Number: 5807-14-7
• Molecular Weight: 139.20
• Beilstein: 3242
• EC Number: 227-367-1
• MDL number: MFCD00043003
• UNSPSC 코드: 12352100
• PubChem Substance ID: 24861334
• NACRES: NA.22

속성

• Quality Level: 200
• 분석: 98%
• 양식: crystals
• mp: 125-130 °C (lit.)
• solubility: acetonitrile: soluble; ethanol: soluble; organic solvents: soluble; water: soluble
• SMILES string: C1CNC2=NCCCN2C1
• InChI: 1S/C7H13N3/c1-3-8-7-9-4-2-6-10(7)5-1/h1-6H2,(H,8,9)
• InChI key: FVKFHMNJTHKMRX-UHFFFAOYSA-N

설명

일반 설명

1,5,7-Triazabicyclo[4.4.0]dec-5-ene, a bicyclic guanidine base, has been found to be an excellent catalyst for Michael and Michael-type reactions. It forms 1:1 complex with lasalocid acid and crystal structure of the complex has been studied by X-ray diffraction, FT-IR spectroscopy and ¹H NMR.

애플리케이션

1,5,7-Triazabicyclo[4.4.0]dec-5-ene may be used as organocatalyst for aminolysis of esters. It may be used as catalyst for direct addition of P(O)-H bonds (dialkyl phosphites and diphenyl phosphonite) across various activated alkenes. Polymer supported 1,5,7-triazabicyclo[4.4.0]dec-5-ene (PTBD) was used as a base and a reagent scavenger for the synthesis of aryl ethers from phenols and alkyl or aryl halides.

안전성 정보

• 픽토그램: GHS05
• 신호어: Danger
• 유해 및 위험 성명서: H314
• 예방조치 성명서: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Hazard Classifications: Skin Corr. 1B
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges