349720

(3-Carboxypropyl)triphenylphosphonium bromide

98%

• 동의어(들): (4-Hydroxy-4-oxobutyl)triphenylphosphonium bromide
• Linear Formula: HO₂C(CH₂)₃P(C₆H₅)₃Br
• CAS Number: 17857-14-6
• Molecular Weight: 429.29
• MDL number: MFCD00274196
• UNSPSC 코드: 12352002
• PubChem Substance ID: 24861704
• NACRES: NA.22

속성

• Quality Level: 100
• 분석: 98%
• 반응 적합성: reaction type: C-C Bond Formation
• mp: 244-247 °C (lit.)
• 작용기: carboxylic acid; phosphine
• SMILES string: [Br-].OC(=O)CCC[P+](c1ccccc1)(c2ccccc2)c3ccccc3
• InChI: 1S/C22H21O2P.BrH/c23-22(24)17-10-18-25(19-11-4-1-5-12-19,20-13-6-2-7-14-20)21-15-8-3-9-16-21;/h1-9,11-16H,10,17-18H2;1H
• InChI key: NKVJKVMGJABKHV-UHFFFAOYSA-N

설명

애플리케이션

Reactant for preparation of:

• Piperamide analogs as histone deacetylase (HDAC) inhibitors with antitumor activity
• Boron-containing benzoxaboroles as antimalarial agents
• Methyl alkenyl quinolones as antimycobacterial agents
• Solandelactone E via Sharpless epoxidation, Taber cyclopropanation, chemoselective reductions and lithiation-borylation-allylation sequence
• Organotin compounds as antifungal agents
• Oleanolic acid derivatives as inhibitors of protein tyrosine phosphatase 1B for negative regulation of insulin pathway (a promising target for treatment of diabetes and obesity)
• 11-oxa prostaglandin analogs with ocular hypotensive activity

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves