430471

Poly(D,L-lactide-co-glycolide)

ester terminated, M_w 50,000-75,000

• 동의어(들): Lactel^® B6006-1, PLGA
• Linear Formula: [C₃H₄O₂]_x[C₂H₂O₂]_y
• MDL number: MFCD00131930
• UNSPSC 코드: 12162002
• PubChem Substance ID: 24866924
• NACRES: NA.23

속성

• Quality Level: 100
• 양식: amorphous
• 피드(feed) 비율: lactide:glycolide 85:15
• 분자량: M_w 50,000-75,000
• 분해 기간: <6 months
• 점도: 0.55-0.75 dL/g, 0.1 % (w/v) in chloroform(25 °C)
• 전이 온도: T_g 45-50 °C
• solubility: ethyl acetate, chloroform, acetone and THF: soluble
• 저장 온도: 2-8°C
• SMILES string: OCC(O)=O.CC(O)C(O)=O
• InChI: 1S/C3H6O3.C2H4O3/c1-2(4)3(5)6;3-1-2(4)5/h2,4H,1H3,(H,5,6);3H,1H2,(H,4,5)
• InChI key: XBBVURRQGJPTHH-UHFFFAOYSA-N

설명

일반 설명

Characteristic properties of ester terminated poly(D,L-lactide-co-glycolide) (PLGA) are in vivo biodegradability, tunable drug release profile and very high encapsulation capacity.

애플리케이션

PLGA polymers find uses in the production of biodegradable medical sutures and for controlled drug release. PLGA microspheres have been reported for use in controlled release of human growth hormone. Thin membranes of blended polymers constituting of PLGA/polycaprolactone/β-tricalcium phosphate have been used in guided bone regeneration.

특징 및 장점

Controlled release of bioactive agents, sutures and bioabsorbable implantable devices.

물리적 형태

Biocompatible, biodegradable polymer.

법적 정보

Lactel is a registered trademark of Evonik Corp

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)