437786

Diethyl chloromalonate

95%

• Linear Formula: ClCH(CO₂C₂H₅)₂
• CAS Number: 14064-10-9
• Molecular Weight: 194.61
• EC Number: 237-913-0
• MDL number: MFCD00009140
• UNSPSC 코드: 12352100
• PubChem Substance ID: 24867397
• NACRES: NA.22

속성

• Quality Level: 100
• 분석: 95%
• 양식: liquid
• refractive index: n20/D 1.432 (lit.)
• density: 1.204 g/mL at 25 °C (lit.)
• 작용기: chloro; ester
• SMILES string: CCOC(=O)C(Cl)C(=O)OCC
• InChI: 1S/C7H11ClO4/c1-3-11-6(9)5(8)7(10)12-4-2/h5H,3-4H2,1-2H3
• InChI key: WLWCQKMQYZFTDR-UHFFFAOYSA-N

설명

일반 설명

Diethyl chloromalonate (Diethyl α-chloromalonate) is a 2-halo-1,3-dicarbonyl compound. It participates in K₂CO₃-catalyzed domino reactions (Michael alkylation, Mannich alkylation, and aldol alkylation) of salicylic aldehyde derivatives to afford functionalized 2,3-dihydrobenzofurans. It reacts with Cs₂CO₃ in the presence of elemental S₈ or Se_n to afford the corresponding diethyl thioxo- or selenoxomalonates, which can be trapped in situ with various 1,3-dienes.

안전성 정보

• 픽토그램: GHS05,GHS07,GHS09
• 신호어: Danger
• 유해 및 위험 성명서: H314,H335,H400
• 예방조치 성명서: P261 - P271 - P273 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Aquatic Acute 1 - Eye Dam. 1 - Skin Corr. 1B - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point (°F): 235.4 °F - closed cup
• Flash Point (°C): 113 °C - closed cup
• 개인 보호 장비: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter