440191

Hexamethyldisilazane

reagent grade, ≥99%

• 동의어(들): Bis(trimethylsilyl)amine, HMDS
• Linear Formula: (CH₃)₃SiNHSi(CH₃)₃
• CAS Number: 999-97-3
• Molecular Weight: 161.39
• Beilstein: 635752
• EC Number: 213-668-5
• MDL number: MFCD00008259
• UNSPSC 코드: 12352103
• PubChem Substance ID: 24867576
• NACRES: NA.23

속성

• Grade: reagent grade
• Quality Level: 300
• 분석: ≥99%
• 양식: liquid
• refractive index: n20/D 1.407 (lit.)
• bp: 125 °C (lit.)
• SMILES string: C[Si](C)(C)N[Si](C)(C)C
• InChI: 1S/C6H19NSi2/c1-8(2,3)7-9(4,5)6/h7H,1-6H3
• InChI key: FFUAGWLWBBFQJT-UHFFFAOYSA-N

설명

일반 설명

Hexamethyldisilane (HMDS) is a stable and effectivereagent for trimethylsilylation of hydrogen-labile substrates such as alcohols,amines, and carboxylic acids. It is commonly used for the protection of sensitivefunctional groups during chemical synthesis. Owing to its low cost, high vapor pressure, and safety, itis widely used as a precursor in chemical vapor deposition(CVD) reactions.

애플리케이션

Hexamethyldisilane (HMDS) can be used:

• As a silylating agent in the trimethylsilylation of alcohols under nearly neutral reaction conditions.
• To control the molecular weights of polypeptides during ring-opening polymerization of α-amino acid N-carboxyanhydrides.
• To fabricate silicon carbonitride thin films by plasma-enhanced CVD.
• For specimen preparation for scanning electron microscopy and the preparation of trimethylsilyl ethers from hydroxy compounds.

특징 및 장점

• High chemicalstability and low molecular weight
• Nontoxic andcost-effective reagent
• Ammonia is theonly byproduct generated during silylation
• Silylationreaction using HDMS is nearly neutral and does not need any precaution

안전성 정보

• 픽토그램: GHS02,GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H225,H302 + H332,H311,H412
• 예방조치 성명서: P210 - P273 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Flam. Liq. 2
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point (°F): 52.5 °F - closed cup
• Flash Point (°C): 11.4 °C - closed cup
• 개인 보호 장비: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter