447714

Methylenebis(phosphonic dichloride)

97%

• Linear Formula: CH₂[P(O)Cl₂]₂
• CAS Number: 1499-29-2
• Molecular Weight: 249.78
• MDL number: MFCD00013901
• UNSPSC 코드: 12352100
• PubChem Substance ID: 24868355
• NACRES: NA.22

속성

• Quality Level: 200
• 분석: 97%
• 양식: solid
• mp: 102-104 °C (lit.)
• 작용기: phosphine oxide
• SMILES string: ClP(Cl)(=O)CP(Cl)(Cl)=O
• InChI: 1S/CH2Cl4O2P2/c2-8(3,6)1-9(4,5)7/h1H2
• InChI key: VRXYCDTWIOCJBH-UHFFFAOYSA-N

설명

일반 설명

Methylenebis(phosphonic dichloride) is an organophosphorus compound that is commonly used in phosphonylation reactions. It is more reactive and the rate of reaction is faster compared to POCl₃. This is because the phosphorus center is more electrophilic due to the lack of electron back-donation from the CH₂ group.

애플리케이션

Methylenebis(phosphonic dichloride) may be used for the following studies:

• Synthesis of mycophenolic methylenebis(phosphonate) derivatives.
• Phosphonylation of nucleosides.
• Preparation of P,P′-partial esters of methylenebisphosphonic acid.
• Synthesis of symmetrical di- and tetra- esters of methylenebisphosphonic acid.

안전성 정보

• 픽토그램: GHS05
• 신호어: Danger
• 유해 및 위험 성명서: H314
• 예방조치 성명서: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Hazard Classifications: Eye Dam. 1 - Skin Corr. 1B
• 보충제 위험성: EUH014
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges