512125

3-Pyridinylboronic acid

≥95.0%

• 동의어(들): 3-Pyridineboronic acid, 3-Pyridylboronic acid, Dihydroxy(3-pyridyl)borane, Pyridin-3-ylboronic acid
• 실험식(Hill 표기법): C₅H₆BNO₂
• CAS Number: 1692-25-7
• Molecular Weight: 122.92
• MDL number: MFCD00674177
• UNSPSC 코드: 12352103
• PubChem Substance ID: 24873612
• NACRES: NA.22

속성

• Quality Level: 100
• 분석: ≥95.0%
• 양식: solid
• mp: >300 °C (lit.)
• SMILES string: OB(O)c1cccnc1
• InChI: 1S/C5H6BNO2/c8-6(9)5-2-1-3-7-4-5/h1-4,8-9H
• InChI key: ABMYEXAYWZJVOV-UHFFFAOYSA-N

설명

애플리케이션

3-Pyridinylboronic acid can be used as a reagent for:

• Phosphine-free Suzuki-Miyaura cross-coupling reactions.
• Regioselective Suzuki-Miyaura coupling and tandem palladium-catalyzed intramolecular aminocarbonylation and annulation.
• N-arylation using copper acetylacetonate catalyst.
• Copper-mediated cyanation and regioselective cyanation of electron-rich benzenes.

It can also be used to prepare:

• New linear poly(phenylpyridyl) chains by Suzuki coupling.
• Oligopyridyl foldamers as mimics of a-helix twist.
• Many highly significant therapeutic enzymatic and kinase inhibitors and receptor antagonists.
• Pyridine substituted pyridinium N-(2′-azinyl)aminides by reacting with dibromo pyridinium aminides via Suzuki coupling reaction.

기타 정보

Contains varying amounts of anhydride

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)