532851

Methyl 2-iodobenzoate

97%

• 동의어(들): Methyl o-iodobenzoate
• Linear Formula: IC₆H₄CO₂CH₃
• CAS Number: 610-97-9
• Molecular Weight: 262.04
• EC Number: 210-243-6
• MDL number: MFCD00016351
• UNSPSC 코드: 12352100
• PubChem Substance ID: 24877921
• NACRES: NA.22

속성

• Quality Level: 200
• 분석: 97%
• refractive index: n20/D 1.604 (lit.)
• bp: 149-150 °C/10 mmHg (lit.)
• density: 1.784 g/mL at 25 °C (lit.)
• 작용기: ester; iodo
• SMILES string: COC(=O)c1ccccc1I
• InChI: 1S/C8H7IO2/c1-11-8(10)6-4-2-3-5-7(6)9/h2-5H,1H3
• InChI key: BXXLTVBTDZXPTN-UHFFFAOYSA-N

설명

일반 설명

Methyl 2-iodobenzoate can be prepared from 2-iodobenzoic acid via esterification. It undergoes cobalt-catalyzed cyclization with aldehydes to form phthalide derivatives. The microbial dihydroxylation of methyl 2-iodobenzoate forms a nonracemic iodocyclohexene carboxylate intermediate. This intermediate forms the precursor for preparing kibdelone C.

애플리케이션

Methyl 2-iodobenzoate may be used in the preparation of:

• N-substituted 4-methylene-3,4-dihydro-1(2H)-isoquinolin-1-ones
• methyl diphenylacetylene-2-carboxylate
• methyl 2-heptynylphenylbenzoate
• (E)-2-[3-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-oxopropyl]benzoic acid methyl ester
• 4-(2-carbomethoxyphenyl)-3-(1-methylethoxy)cyclobut-3-ene-1,2-dione
• 3-(2-carbomethoxyphenyl)-4-methylcyclobuten-3-ene-1,2-dione 2-(ethylene acetal)

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type ABEK (EN14387) respirator filter