681059

2-Methyl-6-nitrobenzoic anhydride

97%

• 동의어(들): MNBA
• 실험식(Hill 표기법): C₁₆H₁₂N₂O₇
• CAS Number: 434935-69-0
• Molecular Weight: 344.28
• MDL number: MFCD06797117
• UNSPSC 코드: 12352108
• PubChem Substance ID: 24885612
• NACRES: NA.22

속성

• Quality Level: 200
• 분석: 97%
• 양식: solid
• mp: 173-177 °C
• 작용기: anhydride; ester; nitro
• SMILES string: Cc1cccc(c1C(=O)OC(=O)c2c(C)cccc2[N+]([O-])=O)[N+]([O-])=O
• InChI: 1S/C16H12N2O7/c1-9-5-3-7-11(17(21)22)13(9)15(19)25-16(20)14-10(2)6-4-8-12(14)18(23)24/h3-8H,1-2H3
• InChI key: YEKPNMQQSPHKBP-UHFFFAOYSA-N

설명

일반 설명

2-Methyl-6-nitrobenzoic anhydride is a reagent employed as a coupling promoter in the synthesis of amides, lactones, esters, and peptides.

애플리케이션

2-Methyl-6-nitrobenzoic anhydride can be used:

• As a versatile lactonization reagent applicable in the preparation of varieties of macrolide natural products and lactones.
• As a reaction promoter in the synthesis of carboxamide derivatives by using corresponding amines and carboxylic acids.
• In the total synthesis of GRP78 inhibitor prunustatin A, antifungal compound (3R,16E,20E,23R)-(−)-eushearilide and an antiobestic drug tetrahydrolipstatin.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves