718742

BrettPhos

98%

• 동의어(들): 2-(Dicyclohexylphosphino)3,6-dimethoxy-2′,4′,6′-triisopropyl-1,1′-biphenyl
• 실험식(Hill 표기법): C₃₅H₅₃O₂P
• CAS Number: 1070663-78-3
• Molecular Weight: 536.77
• MDL number: MFCD11973797
• UNSPSC 코드: 12352112
• PubChem Substance ID: 329763602
• NACRES: NA.22

속성

• Quality Level: 300
• 분석: 98%
• 양식: solid
• 반응 적합성: reaction type: Cross Couplings; reagent type: ligand; reaction type: Buchwald-Hartwig Cross Coupling Reaction; reagent type: ligand; reaction type: Fluorinations
• 환경친화적 대안 제품 점수: old score: 8; new score: 1; Find out more about DOZN™ Scoring
• 환경친화적 대안 제품 특성: Waste Prevention; Atom Economy; Design for Energy Efficiency; Learn more about the Principles of Green Chemistry.
• sustainability: Greener Alternative Product
• mp: 187-195 °C
• 작용기: phosphine
• 환경친화적 대안 카테고리: , Re-engineered
• SMILES string: COc1c(P(C2CCCCC2)C3CCCCC3)c(c4c(C(C)C)cc(C(C)C)cc4C(C)C)c(OC)cc1
• InChI: 1S/C35H53O2P/c1-23(2)26-21-29(24(3)4)33(30(22-26)25(5)6)34-31(36-7)19-20-32(37-8)35(34)38(27-15-11-9-12-16-27)28-17-13-10-14-18-28/h19-25,27-28H,9-18H2,1-8H3
• InChI key: WDVGNXKCFBOKDF-UHFFFAOYSA-N

설명

일반 설명

We are committed to bringing you Greener Alternative Products, which adhere to one of the four categories of Greener Alternatives . This product belongs to category of Re-engineered products, showing key improvements in Green Chemistry Principles “Waste Prevention”, “Atom Economy” and “Design for Energy Efficiency”. Click here to view its DOZN scorecard.

애플리케이션

Buchwald Phosphine Ligands for chemical Synthesis

BrettPhos is a dialkylbiaryl phosphine ligand developed by the Buchwald group. It promotes cross-coupling reactions more efficiently and exhibits improved reactivity compared to other catalytic systems.
It can be used in:

• palladium-catalyzed trifluoromethylation of aryl chlorides
• Buchwald-Hartwig amination
• synthesis of 4-aryl and alkyl substituted, N⁶-alkylated pyridazine-3,6-diamines via a Buchwald protocol

For small scale and high throughput uses, product is also available as ChemBeads (928348)

특징 및 장점

• White crystalline solid
• Air- and moisture-stable
• Thermally stable
• Highly efficient
• Wide functional group tolerance
• Excellent selectivity and conversion

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: nwg
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable