798444

Endo-4-Methoxyphenyl Kwon [2.2.1] Bicyclic Phosphine

• 동의어(들): (1S,4S,5S)-5-(4-methoxyphenyl)-2-tosyl-2-aza-5-phosphabicyclo[2.2.1]heptane
• 실험식(Hill 표기법): C₁₉H₂₂NO₃PS
• Molecular Weight: 375.42
• MDL number: MFCD28016352
• UNSPSC 코드: 12352005
• PubChem Substance ID: 329768650
• NACRES: NA.22

속성

• 양식: powder
• Quality Level: 100
• mp: 156-161 °C
• 작용기: phosphine; sulfonamide
• 저장 온도: 2-8°C
• SMILES string: O=S(N1C[C@H]2[P@@](C3=CC=C(OC)C=C3)C[C@@H]1C2)(C4=CC=C(C)C=C4)=O
• InChI: 1S/C19H22NO3PS/c1-14-3-9-19(10-4-14)25(21,22)20-12-18-11-15(20)13-24(18)17-7-5-16(23-2)6-8-17/h3-10,15,18H,11-13H2,1-2H3
• InChI key: RMFZMNUGIFSNIE-UHFFFAOYSA-N

설명

애플리케이션

The bicyclic, chiral phosphine was developed by the Kwon Research Group.Its initial applications were for asymmetric [3+2] annulation between allenes and imines as well as the first examples of phosphine-catalyzed asymmetric syntheses of 1,2,3,5-substituted pyrrolines. Along with nucleophilic organocatalysis, the P-chiral phosphines may also find utility in asymmetric transition-metal catalysis.

기타 정보

Hydroxyproline-Derived Pseudoenantiomeric [2.2.1] Bicyclic Phosphines: Asymmetric Synthesis of (+)- and (-)-Pyrrolines

Technology Spotlight- Kwon Phosphines: P-Chiral Monodentate Phosphines from Hydroxyproline

Aldrichimica Acta Review- Nucleophilic Chiral Phosphines: Powerful and Versatile Catalysts for Asymmetric Annulations

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable