900892

L-Azidohomoalanine hydrochloride

• 동의어(들): AHA
• 실험식(Hill 표기법): C₄H₈N₄O₂ · HCl
• CAS Number: 942518-29-8
• Molecular Weight: 180.59
• MDL number: MFCD13184931
• UNSPSC 코드: 12352209

속성

• 양식: powder or crystals
• Quality Level: 100
• 반응 적합성: reaction type: click chemistry
• mp: 139 °C
• 저장 온도: −20°C
• SMILES string: [Cl-].[N+H3][C@@H](CCN=[N+]=[N-])C(=O)O
• InChI: 1S/C4H8N4O2.ClH/c5-3(4(9)10)1-2-7-8-6;/h3H,1-2,5H2,(H,9,10);1H/t3-;/m0./s1
• InChI key: MHHYJRIDKLZZEO-DFWYDOINSA-N

설명

애플리케이션

L-Azidohomoalanine (AHA) is an amino acid analog of methionine that contains a very small modification, specifically an azido moiety. This compound can be fed to cultured cells and incorporated into proteins during active protein synthesis. Detection utilizes the chemoselective ligation or “click ” reaction between an azide and an alkyne or cyclooctyne. For example the azido-modified protein can be detected with either fluorescent alkyne or biotin alkyne. Detection sensitivity with these reagents in 1-D gels and Western blots is in the low femtomole range and compatible with downstream LC-MS/MS and MALDI-MS analysis.

안전성 정보

• 픽토그램: GHS02
• 신호어: Danger
• 유해 및 위험 성명서: H242
• 예방조치 성명서: P210 - P234 - P235 - P240 - P370 + P378 - P403
• Hazard Classifications: Self-react. C
• Storage Class Code: 5.2 - Organic peroxides and self-reacting hazardous materials
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable