901609

Diisopropylcarbodiimide solution

1 M in dichloromethane

• 동의어(들): Diisopropylmethanediimine
• Linear Formula: C₇H₁₄N₂
• CAS Number: 693-13-0
• MDL number: MFCD00065689
• UNSPSC 코드: 12352200

속성

• 양식: liquid
• 반응 적합성: reaction type: Coupling Reactions
• 농도: 1 M in dichloromethane
• refractive index: n/D 1.4251
• density: 1.2231
• 응용 분야: peptide synthesis
• InChI: 1S/C7H14N2/c1-6(2)8-5-9-7(3)4/h6-7H,1-4H3
• InChI key: BDNKZNFMNDZQMI-UHFFFAOYSA-N

설명

일반 설명

DIC is an abbreviated form of N,N′-diisopropylcarbodiimide. It plays a role in the cyclization of N-(β-hydroxy)amides to form 2-oxazolines.

애플리케이션

• Alternative to dicyclohexylcarbodiimide in peptide synthesis.
• Coupling reagent for peptide syntheses.
• DIC (N,N′-Diisopropylcarbodiimide) has been used in combination with 1-hydroxy-7-azabenzotriazole (HOAt) for the coupling of amino acid with N-allylglycine to form N-allylpeptide.

Valuable reagent offered as a solution in dichloromethane for more convenient handling.

안전성 정보

• 픽토그램: GHS02,GHS06,GHS08,GHS05
• 신호어: Danger
• 유해 및 위험 성명서: H226,H315,H317,H318,H330,H334,H336,H351
• 예방조치 성명서: P202 - P210 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Inhalation - Carc. 2 - Eye Dam. 1 - Flam. Liq. 3 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• 표적 기관: Central nervous system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point (°F): 91.4 °F
• Flash Point (°C): 33 °C