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907340

Sigma-Aldrich

H-L-Photo-Phe-OH

≥98%

동의어(들):

(S)-2-Amino-3-(4-(3-(trifluoromethyl)-3H-diazirin-3-yl)phenyl)propanoic acid, 4-(Trifluoromethyldiazirin)-L-phenylalanine, Diazirine amino acid, H-Tdf-OH, Photo-Phe, Photo-crosslinking amino acid, Photoprobe building block

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250 MG
CA$200.00

About This Item

실험식(Hill 표기법):
C11H10F3N3O2
CAS Number:
92367-16-3
Molecular Weight:
273.21
MDL number:
MFCD30187606
UNSPSC 코드:
12352101

CA$200.00

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도움 문의

분석

≥98%

양식

powder

반응 적합성

reaction type: solution phase peptide synthesis

재고 정보

available only in USA

응용 분야

peptide synthesis

저장 온도

−20°C

SMILES string

FC(F)(F)C2(N=N2)c1ccc(cc1)CC(N)C(=O)O

InChI

1S/C11H10F3N3O2/c12-11(13,14)10(16-17-10)7-3-1-6(2-4-7)5-8(15)9(18)19/h1-4,8H,5,15H2,(H,18,19)

InChI key

HRGXDARRSCSGOG-UHFFFAOYSA-N

관련 카테고리

유사한 품목 비교

전체 비교 보기

차이점 표시

1 of 4

이 품목
325546449954298158
Dysprosium(III) fluoride anhydrous, powder, ≥99.98% trace rare earth metals basis

450847

Dysprosium(III) fluoride

Dysprosium(III) chloride anhydrous, powder, 99.99% trace metals basis

325546

Dysprosium(III) chloride

Neodymium(III) fluoride anhydrous, powder, 99.99% trace metals basis

449954

Neodymium(III) fluoride

Dysprosium(III) nitrate hydrate 99.9% trace metals basis

298158

Dysprosium(III) nitrate hydrate

form

powder

form

powder

form

powder

form

crystals and lumps

assay

≥99.98% trace rare earth metals basis

assay

99.99% trace metals basis

assay

99.99% trace metals basis

assay

99.9% trace metals basis

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

grade

anhydrous

grade

anhydrous

grade

anhydrous

grade

-

impurities

<100 ppm water

impurities

≤150.0 ppm Trace Rare Earth Analysis

impurities

≤150.0 ppm Trace Rare Earth Analysis

impurities

≤1500.0 ppm Trace Rare Earth Analysis

reaction suitability

reagent type: catalyst
core: dysprosium

reaction suitability

reagent type: catalyst
core: dysprosium

reaction suitability

reagent type: catalyst
core: neodymium

reaction suitability

reagent type: catalyst
core: dysprosium

애플리케이션

H-L-Photo-Phe-OH is a diazirine-containing phenylalanine amino acid and multifunctional
photo-crosslinker. Its incorporation into peptides or small-molecule probes and tools allows for photoaffinity labeling of cellular targets and protein-protein interactions upon UV light (∼360 nm) irradiation to form a covalent bond. This and other multifunctional probe building blocks will continue to accelerate drug discovery research for probing cellular mechanisms, target ID/validation, and understanding traditionally undruggable targets. An Fmoc-protected version is also available as 907294.

Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)

기타 정보

Genetic Incorporation of a Photo-Crosslinkable Amino Acid Reveals Novel Protein Complexes with GRB2 in Mammalian Cells

Trifluoromethyldiazirine: an effective photo-induced cross-linking probe for exploring amyloid formation

A genetically encoded diazirine photo-crosslinker in Escherichia coli

Fishing for Drug Targets: A Focus on Diazirine Photoaffinity Probe Synthesis

Photo-affinity labeling (PAL) in chemical proteomics: a handy tool to investigate protein-protein interactions (PPIs)

픽토그램

Flame
GHS02

신호어

Danger

유해 및 위험 성명서

H242

Hazard Classifications

Self-react. C

Storage Class Code

5.2 - Organic peroxides and self-reacting hazardous materials

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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