911429

Poly(ethylene glycol) methyl ether-block-poly(lactide-co-glycolide)

PEG average M_n 5,000, PLGA average M_n 5,000, lactide:glycolide 80:20

• 동의어(들): PEG-PLGA, PEG5K-PLGA5K, Polyethylene glycol, mPEG-b-PLGA
• Linear Formula: H[(C₃H₄O₂)_x(C₂H₂O₂)_y]_mO[C₂H₄O]_nCH₃
• UNSPSC 코드: 12352112
• NACRES: NA.23

속성

• 양식: powder
• 피드(feed) 비율: lactide:glycolide 80:20
• 분자량: PEG average M_n 5,000 (by NMR); PLGA average M_n 5,000 (by NMR)
• 불순물: ≤500 ppm (GC)
• 색상: white
• 저장 온도: −20°C

설명

애플리케이션

This polymer is a amphiphilic diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PLGA block. This biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). Additionally, well-defined nanoparticles with tunable size and properties can be prepared by altering the molecular weight ratios between hydrophilic and hydrophobic blocks, as well as by controlling formulation parameters.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable