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913839

Sigma-Aldrich

2-Methylnicotinic acid imidazolide

동의어(들):

(1H-imidazol-1-yl)(2-methylpyridin-3-yl)methanone, 1H-Imidazol-1-yl(2-methyl-3-pyridinyl)methanone, 3-(1H-imidazole-1-carbonyl)-2-methylpyridine, NAI, RNA SHAPE probe, RNA structure probe, mNAI

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About This Item

실험식(Hill 표기법):
C10H9N3O
CAS Number:
1055970-47-2
Molecular Weight:
187.20
MDL number:
MFCD25954959
UNSPSC 코드:
12352106
NACRES:
NA.22
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도움 문의

양식

powder

Quality Level

100

mp

68-72 °C

저장 온도

2-8°C

SMILES string

[n]2(cncc2)C(=O)c1c(nccc1)C

InChI

1S/C10H9N3O/c1-8-9(3-2-4-12-8)10(14)13-6-5-11-7-13/h2-7H,1H3

InChI key

OWQPEDNXDCVXJO-UHFFFAOYSA-N

유사한 품목 비교

전체 비교 보기

차이점 표시

1 of 4

이 품목
363138363146363073
Poly(vinyl alcohol) Mw 146,000-186,000, 99+% hydrolyzed

363065

Poly(vinyl alcohol)

Poly(vinyl alcohol) Mw 31,000-50,000, 98-99% hydrolyzed

363138

Poly(vinyl alcohol)

Poly(vinyl alcohol) Mw 85,000-124,000, 99+% hydrolyzed

363146

Poly(vinyl alcohol)

Poly(vinyl alcohol) average Mw 31,000-50,000, 87-89% hydrolyzed

363073

Poly(vinyl alcohol)

form

crystalline powder, crystals

form

powder

form

powder or crystals

form

crystalline powder, crystals or granules

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

mol wt

Mw 146,000-186,000

mol wt

Mw 31,000-50,000

mol wt

Mw 85,000-124,000

mol wt

average Mw 31,000-50,000

falling ball

55-65 cP, 4 % in H2O(20 °C)(lit.)

falling ball

5.4-6.5 cP, 4 % in H2O(20 °C)(lit.)

falling ball

28-32 cP, 4 % in H2O(20 °C)(lit.)

falling ball

5.2-6.2 cP, 4 % in H2O(20 °C)(lit.)

애플리케이션

2-Methylnicotinic acid imidazolide (NAI or mNAI) is an RNA SHAPE probe for live-cell RNA structure profiling. SHAPE -- or selective 2′-hydroxyl acylation analyzed by primer extension -- uses small, electrophilic chemical probes to react with the 2′-hydroxyl group and provides insight to RNA structure and its dynamics in varied cells states or in cells with gene knockouts. It has also been extended to the SHALiPE approach, selective 2′-hydroxyl acylation with lithium ion-based primer extension.

기타 정보

Conditional control of RNA-guided nucleic acid cleavage and gene editing

Guidelines for SHAPE Reagent Choice and Detection Strategy for RNA Structure Probing Studies

SnapShot: RNA Structure Probing Technologies

Structural Analysis using SHALiPE to Reveal RNA G-Quadruplex Formation in Human Precursor MicroRNA

Determination of in vivo RNA structure in low-abundance transcripts

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

  • Specification Sheet

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    시험 성적서(COA)

    Lot/Batch Number
    MKCQ2936

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