925217

TissueFab^® - low endotoxin GelMA-UV bioink

0.2 μm filtered, suitable for 3D bioprinting applications

• 동의어(들): Bioink, GelMA, Gelatin methacrylamide, Gelatin methacrylate, Gelatin methacryloyl
• UNSPSC 코드: 12352201
• NACRES: NA.23

속성

• Quality Level: 100
• 무균: 0.2 μm filtered
• 양식: viscous liquid (to gel)
• 크기: 10 mL
• 불순물: ≤5 CFU/g Bioburden (Fungal); ≤5 CFU/g Bioburden (Aerobic); ≤50 EU/mL Endotoxin
• 색상: pale yellow to colorless
• pH: 6.5-7.5
• 점도: 2-20 cP
• 응용 분야: 3D bioprinting
• 저장 온도: 2-8°C

설명

일반 설명

Gelatin methacryloyl (GelMA) is a polymerizable hydrogel material derived from natural extracellular matrix (ECM) components. Due to its low cost, abundance, and retention of natural cell binding motifs, gelatin has become a highly sought material for tissue engineering applications.

The addition of photocrosslinkable methacrylamide functional groups in GelMA allows the synthesis of biocompatible, biodegradable, and non-immunogenic hydrogels that are stable in biologically relevant conditions and promote cell adhesion, spreading, and proliferation.

Temporal and spatial control of the crosslinking reaction can be obtained by adjusting the degree of functionalization and polymerization conditions, allowing for the fabrication of hydrogels with unique patterns, 3D structures, and morphologies.

애플리케이션

Gelatin methacrylate based bioinks have been used in the following bioprinting applications:

• osteogenic,
• chondrogenic ,
• hepatic ,
• adipogenic ,
• vasculogenic ,
• epithelial ,
• endothelial ,
• cardiac valve ,
• skin ,
• tumors

특징 및 장점

• Ready-to-use formulation optimized for high printing fidelity and cell viability, eliminating the lengthy bioink formulation development process
• Step-by-step protocols developed and tested by MilliporeSigma 3D Bioprinting Scientists, no prior 3D bioprinting experience neede
• Suitable for different extrusion-based 3D bioprinter model
• Methacrylamide functional group can also be used to control the hydrogel physical parameters such as pore size, degradation rate, and swell ratio.

법적 정보

TISSUEFAB is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3