810220P

C6-NBD Galactosyl Ceramide

Avanti Research^™ - A Croda Brand 810220P, powder

• 동의어(들): N-[6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl]-D-galactosyl-β1-1′-sphingosine
• 실험식(Hill 표기법): C₃₆H₅₉N₅O₁₁
• CAS Number: 170212-26-7
• Molecular Weight: 737.88
• MDL number: MFCD03453619
• UNSPSC 코드: 12352211
• NACRES: NA.25

속성

• 분석: >99% (TLC)
• 양식: powder
• 포장: pkg of 1 × 250 μg (810220P-250ug)
• 제조업체/상표: Avanti Research^™ - A Croda Brand 810220P
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: [N+](=O)([O-])c1c2n[o]nc2c(cc1)NCCCCCC(=O)N[C@H]([C@H](O)\C=C\CCCCCCCCCCCCC)CO[C@@H]3O[C@@H]([C@@H]([C@@H]([C@H]3O)O)O)CO
• InChI: 1S/C36H59N5O11/c1-2-3-4-5-6-7-8-9-10-11-12-13-15-18-28(43)26(24-50-36-35(47)34(46)33(45)29(23-42)51-36)38-30(44)19-16-14-17-22-37-25-20-21-27(41(48)49)32-31(25)39-52-40-32/h15,18,20-21,26,28-29,33-37,42-43,45-47H,2-14,16-17,19,22-24H2,1H3,(H,38,44)/b18-15
• InChI key: ZYEQNDHFYIPTAY-LFUFHFQKSA-N

설명

일반 설명

C6-NBD Galactosyl Ceramide is a fluorescent analog of the sphingolipid, galactosyl ceramide. Its fluorescent property is due to presence of NBD (2-(4-nitro-2,1,3-benzoxadiazol-7-yl) aminoethyl) group.

애플리케이션

C6-NBD Galactosyl Ceramide is suitable for use as a substrate in neutral β-glycosylceramidase (GCase) activity assay.

생화학적/생리학적 작용

Galactosyl ceramide is also known as galactocerebroside and is produced in the lumen of the endoplasmic reticulum. Galactosyl ceramide is a vaccine adjuvant, it stimulates natural killer T (NKT) cells to increase secretion of T helper type 1 (Th1) and T-helper type 2 (TH2) cytokines. Galactosyl ceramide accumulation in excess is responsible for diseases such as Krabbe′s disease. Galactocerebroside is a precursor of 3′-sulfo-galactosylceramide, a vital sulfoglycolipid found in the brain and other organs.

포장

5 mL Amber Glass Screw Cap Vial (810220P-250ug)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

안전성 정보

• Storage Class Code: 11 - Combustible Solids