857324P

17:0 Cyclic LPA

Avanti Research^™ - A Croda Brand 857324P, powder

• 동의어(들): 1-heptadecanoyl-glycero-2,3-cyclic-phosphate (ammonium salt)
• 실험식(Hill 표기법): C₂₀H₄₂NO₆P
• CAS Number: 2260669-82-5
• Molecular Weight: 423.52
• UNSPSC 코드: 51191904
• NACRES: NA.25

속성

• 분석: >99% (TLC)
• 양식: powder
• 포장: pkg of 1 × 1 mg (857324P-1mg)
• 제조업체/상표: Avanti Research^™ - A Croda Brand 857324P
• 지질 유형: phospholipids; cardiolipins
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: O=P1([O-])O[C@H](COC(CCCCCCCCCCCCCCCC)=O)CO1.[NH4+]
• InChI: 1S/C20H39O6P.H3N/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20(21)24-17-19-18-25-27(22,23)26-19;/h19H,2-18H2,1H3,(H,22,23);1H3/t19-;/m1./s1
• InChI key: QQOXNBRKDUFLHW-FSRHSHDFSA-N

설명

일반 설명

Cyclic phosphatidic acid (cPA) is a naturally occurring analog of the growth factor-like phospholipid mediator, lysophosphatidic acid (LPA). The sn-2 hydroxy group of CPA forms a 5-membered ring with the sn-3 phosphate.

애플리케이션

17:0 Cyclic LPA or 1-heptadecanoyl-glycero-2,3-cyclic-phosphate (ammonium salt) has been used as an internal standard for the quantification of cyclic lysophosphatidic acid (LPA) esters in proton samples using reversed-phase ultra-performance liquid chromatography-tandem mass spectrometer (UPLC-MS/MS).

생화학적/생리학적 작용

cPA affects numerous cellular functions, including anti-mitogenic regulation of the cell cycle, induction of stress fiber formation, inhibition of tumor cell invasion and metastasis, and regulation of differentiation and survival of neuronal cells.
Interestingly, many of these cellular responses caused by cPA oppose those of LPA despite the activation of apparently overlapping receptor populations.

포장

5 mL Amber Glass Screw Cap Vial (857324P-1mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• Flash Point (°F): No data available
• Flash Point (°C): No data available