860461P

N-C12-desoxymethylsphinganine

N-lauroyl-1-desoxymethylsphinganine (m17:0/12:0), powder

• 동의어(들): N-dodecanoyl-1-desoxymethylsphinganine (m17:0/12:0); N-C12-1-desoxyMeDHCer; 110959
• 실험식(Hill 표기법): C₂₉H₅₉NO₂
• CAS Number: 1246298-41-8
• Molecular Weight: 453.78
• MDL number: MFCD00066101
• UNSPSC 코드: 12352211
• NACRES: NA.25

속성

• 분석: >99% (TLC)
• 양식: powder
• 포장: pkg of 1 × 1 mg (860461P-1mg)
• 제조업체/상표: Avanti Research^™ - A Croda Brand 860461P
• 지질 유형: sphingolipids; bioactive lipids
• 배송 상태: dry ice
• 저장 온도: −20°C

설명

일반 설명

Commonly referred to as 1-desoxymethyldihydroceramide (1-desoxyMeDHCer), this product is the N-acylated form of 1-desoxymethylsphinganine, a potent inhibitor of sphingolipid metabolism. The biological activity of 1-desoxyMeDHCer is not clearly understood at this time.

N-C12-desoxymethylsphinganine commonly referred to as 1-deoxydihydroceramide (1-deoxyDHCer), is the N-acylated form of 1-deoxysphinganine, a potent inhibitor of sphingolipid metabolism.

생화학적/생리학적 작용

Ceramide synthases (CerS) catalyzes the acylation of sphingoid bases using fatty acyl-CoA and its inhibition results in decrease of desoxymethylsphinganine (N-acylsphinganines (dihydroceramides)) levels and accumulation of sphinganine (Sa). Dihydroceramides (DHCer) are intermediates of ceramide biosynthesis.

포장

5 mL Amber Glass Screw Cap Vial (860461P-1mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3