860473P

1-desoxymethylsphinganine

Avanti Research^™ - A Croda Brand 860473P, powder

• 동의어(들): 1-desoxymethylsphinganine (m17:0)
• 실험식(Hill 표기법): C₁₇H₃₇NO
• CAS Number: 1219484-98-6
• Molecular Weight: 271.48
• MDL number: MFCD28143634
• UNSPSC 코드: 12352211
• NACRES: NA.25

속성

• 양식: powder
• 포장: pkg of 1 × 1 mg (860473P-1mg)
• 제조업체/상표: Avanti Research^™ - A Croda Brand 860473P
• 지질 유형: bioactive lipids; sphingolipids
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: NC[C@]([H])(O)CCCCCCCCCCCCCCC
• InChI key: UGVBFHUWZNNKIK-QGZVFWFLSA-N

설명

일반 설명

1-desoxymethylsphinganine is synthesized by the condensation of alanine with palmitoyl-CoA.

애플리케이션

1-desoxymethylsphinganine is suitable for use for testing its cytotoxic effects on primary neuron-glia cultures. It is also suitable for use as a neurotoxic agent in human CD8⁺ T cells. In hereditary sensory and autonomic neuropathy type I, mutations in serine palmitoyltransferase long chain base subunit 1 resulting in altered substrate specificity and accumulation of 1.

생화학적/생리학적 작용

1-desoxymethylsphinganine is neurotoxic towards CD8⁺ T cells and inhibits cytokine production. However, it is not cytotoxic to dopaminergic neurons.

포장

5 mL Amber Glass Screw Cap Vial (860473P-1mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3