860506P

C6 Ceramide (d18:1/6:0)

Avanti Research^™ - A Croda Brand

• 동의어(들): N-hexanoyl-D-erythro-sphingosine
• 실험식(Hill 표기법): C₂₄H₄₇NO₃
• CAS Number: 124753-97-5
• Molecular Weight: 397.63
• MDL number: MFCD00870174
• UNSPSC 코드: 12352211
• NACRES: NA.25

속성

• 양식: powder
• 포장: pkg of 1 × 10 mg (860506P-10mg); pkg of 1 × 5 mg (860506P-5mg)
• 제조업체/상표: Avanti Research^™ - A Croda Brand
• 지질 유형: sphingolipids
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: OC[C@]([H])(NC(CCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC
• InChI: 1S/C24H47NO3/c1-3-5-7-8-9-10-11-12-13-14-15-16-18-19-23(27)22(21-26)25-24(28)20-17-6-4-2/h18-19,22-23,26-27H,3-17,20-21H2,1-2H3,(H,25,28)/b19-18+
• InChI key: NPRJSFWNFTXXQC-VHEBQXMUSA-N

설명

일반 설명

C6 Ceramide (d18:1/6:0) is a short chain and a cell permeable ceramide. It comprises amino alcoholic chain attached to fatty acyl chain via an amide linkage.

애플리케이션

C6 Ceramide (d18:1/6:0) has been used as a chemotherapeutic agent to test its anti-tumor effect in breast cancer cells and ovarian cancer cell lines. It has also been used to test chemo-sensitization effects in cancer cells.

생화학적/생리학적 작용

C6 Ceramide (d18:1/6:0) is involved in inhibiting proliferation and inducing apoptosis. When used in combination with acid ceramidase inhibitor DM102, [(2R,3Z)-N-(1-hydroxyoctadec-3-en-2-yl)pivaloylamide], it favors cell death in human breast cancer cells lines. C6 Ceramide may serve as an adjunct in chemotherapy. It elicits anti-tumor effects via AKT (serine/threonine-specific protein kinase) dephosphorylation and α-tubulin acetylation.

포장

5 mL Amber Glass Screw Cap Vial (860506P-10mg)

5 mL Amber Glass Screw Cap Vial (860506P-5mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable