860627P

C18 Dihydroceramide (d18:0/18:0)

Avanti Research^™ - A Croda Brand 860627P, powder

• 동의어(들): N-stearoyl-D-erythro-sphinganine
• 실험식(Hill 표기법): C₃₆H₇₃NO₃
• CAS Number: 2304-80-5
• Molecular Weight: 567.97
• MDL number: MFCD01076443
• UNSPSC 코드: 12352211
• NACRES: NA.25

속성

• 양식: powder
• 포장: pkg of 1 × 25 mg (860627P-25mg); pkg of 1 × 5 mg (860627P-5mg)
• 제조업체/상표: Avanti Research^™ - A Croda Brand 860627P
• 지질 유형: sphingolipids
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: OC[C@]([H])(NC(CCCCCCCCCCCCCCCCC)=O)[C@]([H])(O)CCCCCCCCCCCCCCC
• InChI: 1S/C36H73NO3/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-36(40)37-34(33-38)35(39)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h34-35,38-39H,3-33H2,1-2H3,(H,37,40)/t34-,35+/m0/s1
• InChI key: KZTJQXAANJHSCE-OIDHKYIRSA-N

설명

일반 설명

C18 Dihydroceramide (d18:0/18:0) or N-Stearoylsphinganine is a synthetic lipid. Acylation of sphinganine with stearoyl (FA-CoA with C18 acyl chain) by dihydro ceramide synthase 1, yields C18-dihydroceramide.

애플리케이션

C18 Dihydroceramide (d18:0/18:0) has been used as a standard for the quantitation of sphingolipid metabolites in adipose tissues by quadrupole time-of-flight (Q-TOF) mass spectrometry.

생화학적/생리학적 작용

Dihydroceramides act as precursors for ceramides in the mammalian de-novo sphingolipid pathway. vitamin D supplementation increases plasma C18 dihydroceramide (C18-DHC) levels in type 2 diabetes mellitus (T2D) patients. Low serum concentration of C18-DHC has been observed in patients with history of graft rejection and ischemic type biliary lesions (ITBL). Therefore, it can be used as a predictor of graft rejection.

포장

5 mL Amber Glass Screw Cap Vial (860627P-25mg)

5 mL Amber Glass Screw Cap Vial (860627P-5mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

안전성 정보

• Storage Class Code: 11 - Combustible Solids