860812P
Avanti
12:0(2S-OH) Ceramide
Avanti Research™ - A Croda Brand 860812P, powder
동의어(들):
N-(2′-(S)-hydroxylauroyl)-D-erythro-sphingosine
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About This Item
실험식(Hill 표기법):
C30H59NO4
CAS Number:
Molecular Weight:
497.79
MDL number:
UNSPSC 코드:
12352211
NACRES:
NA.25
양식
powder
포장
pkg of 1 × 5 mg (860812P-5mg)
제조업체/상표
Avanti Research™ - A Croda Brand 860812P
지질 유형
sphingolipids
배송 상태
dry ice
저장 온도
−20°C
SMILES string
CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC([C@@H](O)CCCCCCCCCC)=O)CO
InChI
1S/C30H59NO4/c1-3-5-7-9-11-13-14-15-16-17-19-20-22-24-28(33)27(26-32)31-30(35)29(34)25-23-21-18-12-10-8-6-4-2/h22,24,27-29,32-34H,3-21,23,25-26H2,1-2H3,(H,31,35)/b24-22+/t27-,28+,29-/m0/s1
InChI key
CPDJNFOAARXMMT-NGXZUFBYSA-N
일반 설명
Ceramides with 2-hydroxy fatty acids (hFA) group are present in the epidermis. 12:0(2S-OH) Ceramide is a 2S hydroxylated lauric acid-containing ceramide.
생화학적/생리학적 작용
Hydroxy fatty acid (hFA)-sphingolipids facilitate cell signaling. hFA-ceramides contribute to the permeability barrier function of the epidermis. Synthesis of hFA-ceramides are catalyzed by fatty acid 2-hydroxylase (FA2H). Mutations of FA2H causes nervous system disorders leukodystrophy and spastic paraparesis in humans. An antitumor drug, PM02734 requires hFA-ceramides in the cell membrane to exhibit its activity.
포장
5 mL Amber Glass Screw Cap Vial (860812P-5mg)
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
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