890700P

12:0 EPC (Cl Salt)

Avanti Research^™ - A Croda Brand 890700P, powder

• 동의어(들): 1,2-dilauroyl-sn-glycero-3-ethylphosphocholine (chloride salt)
• 실험식(Hill 표기법): C₃₄H₆₉NO₈PCl
• CAS Number: 474945-22-7
• Molecular Weight: 686.34
• MDL number: MFCD22495356
• UNSPSC 코드: 12352211
• NACRES: NA.25

속성

• 양식: powder
• 포장: pkg of 1 × 10 mg (890700P-10mg)
• 제조업체/상표: Avanti Research^™ - A Croda Brand 890700P
• 지질 유형: cationic lipids; transfection
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: O=P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O)OCC.[Cl-]
• InChI: 1S/C34H69NO8P.ClH/c1-7-10-12-14-16-18-20-22-24-26-33(36)39-30-32(31-42-44(38,40-9-3)41-29-28-35(4,5)6)43-34(37)27-25-23-21-19-17-15-13-11-8-2;/h32H,7-31H2,1-6H3;1H/q+1;/p-1/t32-,44?;/m1./s1
• InChI key: QWVQEMZYQQUQCH-XFSYIJCRSA-M

설명

일반 설명

1,2-dilauroyl-sn-glycero-3-ethylphosphocholine (12:0 EPC) is a cationic phospholipid. 12:0 EPC is a short-chain analog of dioleoyl ethylphosphatidylcholine. O-alkyl phosphatidylcholines constitute the first chemically stable triesters of biological lipid structures and the first cationic derivatives of phospholipids consisting entirely of biological metabolites linked with ester bonds. The lipid has low toxicity and is biodegradable.

애플리케이션

1,2-dilauroyl-sn-glycero-3-ethylphosphocholine (12:0 EPC (Cl Salt)) is suitable for use in lipoplex preparation and to study the lipoplex transfection activity. It might also be used in lipid mixtures to study its cubic phases of formation, stability and phase transitions.

생화학적/생리학적 작용

1,2-dilauroyl-sn-glycero-3-ethylphosphocholine (12:0 EPC) is preferred for transfection of cultured primary endothelial cells. 12:0 EPC forms lamellar lipoplexes possessing high to superior transfection activity. Chemically synthesized cationic lipids are applicable as non-viral gene carriers. Variation in the hydrocarbon chain of phosphatidylcholine (PC) derivatives affects transfection efficiency.

포장

5 mL Clear Glass Sealed Ampule (890700P-10mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3