999989C

18:1 Diether PC

1,2-di-O-(9Z-octadecenyl)-sn-glycero-3-phosphocholine, chloroform

• 동의어(들): Dioctadecenyl PC
• 실험식(Hill 표기법): C₄₄H₈₈NO₆P
• CAS Number: 105370-99-8
• Molecular Weight: 758.15
• MDL number: MFCD28143676
• UNSPSC 코드: 51191904
• NACRES: NA.25

속성

• 양식: liquid
• 포장: pkg of 1 × 1 mL (999989C-10mg)
• 제조업체/상표: Avanti Research^™ - A Croda Brand 999989C
• 농도: 10 mg/mL (999989C-10mg)
• 지질 유형: phospholipids; cardiolipins
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OCCCCCCCC/C=C\CCCCCCCC)COCCCCCCCC/C=C\CCCCCCCC)=O
• InChI: 1S/C44H88NO6P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-39-48-42-44(43-51-52(46,47)50-41-38-45(3,4)5)49-40-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h20-23,44H,6-19,24-43H2,1-5H3/b22-20-,23-21-/t44-/m1/s1
• InChI key: RBPWQIKZHBYIEY-PXCYNBOKSA-N

설명

일반 설명

18:1 Diether PC (phosphocholine) is a class of glycerophospholipids that has two octadecene chains attached to the sn-1 and sn-2 positions of the glycerol backbone by ether bonds. It has choline as the alcohol moiety, attached to the phosphate group.

애플리케이션

18:1 Diether PC or 1,2-di-O-(9Z-octadecenyl)-sn-glycero-3-phosphocholine might be used:

• to prepare proteoliposomes to investigate the effects of ceramide and ceramide phosphate/ for the determination of phospholipase A activity of lecithin-cholesterol acyltransferase (LCAT) in the ether matrix
• to prepare lipid bilayer membrane to study the influence of glutamic acid residues and pH on the properties of transmembrane helices
• in large unilamellar vesicles (LUVs) to explore the differential interaction of pH (low) insertion peptide (pHLIP) with it by utilizing fluorescence and circular dichroism (CD) spectroscopic approaches

생화학적/생리학적 작용

Lipids prepared using 18:1 Diether PC (phosphocholine), are found to be more stable than the natural ester lipids under alkaline conditions.

포장

5 mL Clear Glass Sealed Ampule (999989C-10mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

안전성 정보

• 픽토그램: GHS06,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• 예방조치 성명서: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• 표적 기관: Central nervous system, Liver,Kidney
• WGK: WGK 3