05-1529

Anti-FXR1 Antibody, clone 6BG10

clone 6BG10, from mouse

• 동의어(들): fragile X mental retardation, autosomal homolog 1, fragile X mental retardation-related protein 1
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 항체 형태: purified antibody
• 항체 생산 유형: primary antibodies
• 클론: 6BG10, monoclonal
• 종 반응성: mouse, human
• 기술: immunocytochemistry: suitable; immunoprecipitation (IP): suitable; western blot: suitable
• 동형: IgG2aκ
• NCBI 수납 번호: NP_001013456.1
• UniProt 수납 번호: P51114
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... FXR1(8087)

설명

일반 설명

Fragile X mental retardation-related protein 1 (FXR1) and FXR2 are members of the FMR1 family sharing a very high degree of protein similarity among them. They interact with each other and also with FMR1, moving between the cytoplasm and the nucleus. FXR1 is an RNA binding protein and is expressed in the heart, kidney, brain, and testis. Mutations in FMR1 result in the most common form of mental retardation.

특이성

This antibody recognizes FXR1.

면역원

Epitope: Unknown

Recombinant protein corresponding to human FXR1.

애플리케이션

Immunocytochemistry Analysis: 1:500 dilution from a representative lot detected FXR1 in HeLa and NIH/3T3 cell lysates.

Immunoprecipitation Analysis: A representative lot was used in an independent laboratory in immunoprecipitation. Siomi, M., et al. (1996). Molecular and Cellular Biology. 3825-3832.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
RNA Metabolism & Binding Proteins

Developmental Signaling

Use Anti-FXR1 Antibody, clone 6BG10 (Mouse Monoclonal Antibody) validated in WB, ICC, IP to detect FXR1 also known as fragile X mental retardation autosomal homolog 1.

품질

Evaluated by Western Blot in HeLa cell lysate.

Western Blot Analysis: 0.5 µg/ml of this antibody detected FXR1 on 10 µg of HeLa cell lysate.

표적 설명

68 kDa

물리적 형태

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

분석 메모

Control
HeLa cell lysate

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable