12-533

GSM (GSK3 substrate peptide)

• 동의어(들): GSK3 Substrate Peptide, GSM Peptide, Substrate for GSK3
• UNSPSC 코드: 12352200
• eCl@ss: 32160405
• NACRES: NA.41

속성

• 분자량: M_w 2673 Da
• Quality Level: 100
• 제조업체/상표: Upstate^®
• 기술: activity assay: suitable (kinase)
• NCBI 수납 번호: NM_019884.2
• UniProt 수납 번호: P49840
• 배송 상태: dry ice

설명

애플리케이션

GSM (GSK3 substrate peptide) has been used:

• in in vitro glycogen synthase kinase 3 (GSK-3)-3β activity assay to measure the kinase activity of GSK-3
• as a supplement in perfusates in kinase activity assay to determine the effect of the phosphatase-activating domain (PAD) peptide on squid axoplasm
• as a control in Kinase-Glo luminescent kinase assay to measure the influence of ibuprofen treatment on the catalytic activity of the kinase GSK3β

생화학적/생리학적 작용

Glycogen synthase kinase 3 (GSK3) is a protein kinase, which regulates glycogen metabolism. It regulates various cell functions, like signaling by insulin, growth factors and nutrients, and the specification of cell fates during embryonic development. GSK3 is involved modulating in apoptosis, cell division, and microtubule function.

품질

Routinely evaluated as a substrate for GSK3β (Catalog # 14-306).

물리적 형태

1 mg of GSM lyophilized from 1 mL sterile, distilled water. Lyophilized powder.

저장 및 안정성

Lyophilized: 2 years at -20°C. Rehydrated: 6 months at -20°C

법적 정보

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable