242284

Aniline

ACS reagent, ≥99.5%

• 동의어(들): Aminobenzene, Benzenamine
• Linear Formula: C₆H₅NH₂
• CAS Number: 62-53-3
• Molecular Weight: 93.13
• Beilstein: 605631
• EC Number: 200-539-3
• MDL number: MFCD00007629
• UNSPSC 코드: 12352100
• eCl@ss: 39030407
• PubChem Substance ID: 24854547
• NACRES: NA.21
• bp: 184 °C (lit.)
• vapor pressure: 0.7 mmHg ( 25 °C)

속성

• Grade: ACS reagent
• Quality Level: 200
• vapor density: 3.22 (185 °C, vs air)
• vapor pressure: 0.7 mmHg ( 25 °C)
• 분석: ≥99.5%
• 양식: liquid
• autoignition temp.: 1139 °F
• expl. lim.: 11 %
• dilution: (for analytical testing)
• 불순물: Hydrocarbons, passes test; Nitrobenzene, passes test (lim. ~0.001%); ≤0.01% chlorobenzene
• 무기 잔류물: ≤0.005%
• refractive index: n20/D 1.586 (lit.)
• bp: 184 °C (lit.)
• mp: −6 °C (lit.)
• solubility: water: soluble
• density: 1.022 g/mL at 25 °C (lit.)
• SMILES string: Nc1ccccc1
• InChI: 1S/C6H7N/c7-6-4-2-1-3-5-6/h1-5H,7H2
• InChI key: PAYRUJLWNCNPSJ-UHFFFAOYSA-N

설명

애플리케이션

Aniline is an aromatic primary amine that may be used as a reactant in the synthesis of organic intermediates such as 3-chloro-N-phenyl-pyridin-2-amine, (Z)-methyl 3-(phenylamino)but-2-enoate, 2-iodo-N-phenylbenzamide, 2,4-dichloroquinoline and N-(2-propynyl)aniline.

생화학적/생리학적 작용

The acute toxicity of aniline involves its activation in vivo to 4-hydroxyaniline and the formation of adducts with hemoglobin. In erythrocytes, this is associated with the release of iron and the accumulation of methemoglobin and the development of hemolytic anemia and inflammation of the spleen. Tumor formation is often observed in the spleen on prolonged administration.

물리적 특성

Material darkens in storage to reddish-brown with no loss in purity.

안전성 정보

• 픽토그램: GHS06,GHS08,GHS05,GHS09
• 신호어: Danger
• 유해 및 위험 성명서: H301 + H311 + H331,H317,H318,H341,H351,H372,H410
• 예방조치 성명서: P273 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Eye Dam. 1 - Muta. 2 - Skin Sens. 1 - STOT RE 1
• 표적 기관: Blood
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point (°F): 158.0 °F - closed cup
• Flash Point (°C): 70 °C - closed cup
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter