60063

Potassium antimonyl tartrate trihydrate

purum p.a., 99.0-103% (RT)

• 동의어(들): Antimony potassium tartrate trihydrate, Tartar emetic
• 실험식(Hill 표기법): C₈H₄K₂O₁₂Sb₂ · 3H₂O
• CAS Number: 28300-74-5
• Molecular Weight: 667.87
• EC Number: 234-293-3
• MDL number: MFCD00167056
• UNSPSC 코드: 12352100
• PubChem Substance ID: 57651716
• NACRES: NA.21

속성

• grade: purum p.a.
• Quality Level: 200
• 분석: 99.0-103% (RT)
• 손실: ≤2.7% loss on drying
• mp: ≥300 °C (lit.)
• 음이온 미량물: chloride (Cl^-): ≤100 mg/kg; sulfate (SO₄^2-): ≤500 mg/kg
• 양이온 미량물: Ca: ≤50 mg/kg; Cd: ≤50 mg/kg; Co: ≤50 mg/kg; Cu: ≤50 mg/kg; Fe: ≤50 mg/kg; Na: ≤500 mg/kg; Ni: ≤50 mg/kg; Pb: ≤50 mg/kg; Zn: ≤50 mg/kg
• SMILES string: O.O.O.[K+].[K+].O=C1O[Sb-]23OC1C4O[Sb-]5(OC(C(O2)C(=O)O3)C(=O)O5)OC4=O
• InChI: 1S/2C4H4O6.2K.3H2O.2Sb/c2*5-1(3(7)8)2(6)4(9)10;;;;;;;/h2*1-2H,(H,7,8)(H,9,10);;;3*1H2;;/q2*-2;2*+1;;;;2*+3/p-4
• InChI key: WBTCZEPSIIFINA-UHFFFAOYSA-J

설명

일반 설명

Potassium antimonyl tartrate trihydrate is a trivalent antimony compound. It has been reported to be a leishmanicidal compound and exhibits more toxic action than pentavalent antimony (Pentostam) against Leishmania species. Three-dimensional X-ray and white radiation neutron diffraction methods have been reported to investigate the crystal structure of its optically active form (dipotassium di-μ-d-tartrato (4)-bis(antimonate(III)) trihydrate). Unit cell dimensions reported were: a = 11.192(2), b = 11.696(3), and c = 25.932(5)Å.

애플리케이션

Potassium antimonyl tartrate trihydrate may be used as an Sb(III)-containing drug to investigate its ability to induce cell death associated with DNA fragmentation in axenic amastigotes of Leishmania infantum.

안전성 정보

• 픽토그램: GHS06,GHS09
• 신호어: Danger
• 유해 및 위험 성명서: H301,H315,H317,H332,H411
• 예방조치 성명서: P261 - P273 - P280 - P301 + P310 - P302 + P352 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Aquatic Chronic 2 - Skin Irrit. 2 - Skin Sens. 1
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Faceshields, Gloves