65943

N-Methyl-bis(trifluoroacetamide)

derivatization grade (GC derivatization), LiChropur^™, ≥99.0% (GC)

• 동의어(들): MBTFA
• Linear Formula: CF₃CON(CH₃)COCF₃
• CAS Number: 685-27-8
• Molecular Weight: 223.07
• Beilstein: 1878402
• EC Number: 211-680-5
• MDL number: MFCD00000412
• UNSPSC 코드: 23151817
• PubChem Substance ID: 329760134
• NACRES: NA.22

속성

• Grade: derivatization grade (GC derivatization)
• Quality Level: 100
• 분석: ≥99.0% (GC)
• 품질: LiChropur^™
• 반응 적합성: reagent type: derivatization reagent; reaction type: Acylations; reagent type: derivatization reagent; reaction type: Silylations
• 기술: gas chromatography (GC): suitable
• refractive index: n20/D 1.346 (lit.); n20/D 1.346
• bp: 121-122 °C (lit.)
• density: 1.547 g/mL at 25 °C
• SMILES string: CN(C(=O)C(F)(F)F)C(=O)C(F)(F)F
• InChI: 1S/C5H3F6NO2/c1-12(2(13)4(6,7)8)3(14)5(9,10)11/h1H3
• InChI key: AWGBWLXGUPTXHF-UHFFFAOYSA-N

설명

일반 설명

N-Methyl-bis(trifluoroacetamide) is a common reagent used in the alkylation process, which targets highly polar, multi-functional compounds such as carbohydrates and amino acids.

애플리케이션

N-Methyl-bis(trifluoroacetamide) may be used as an on-column derivatization agent for the determination of amphetamine-type stimulants in biological samples, and ketamine, norketamine, dehydronorketamine in urine samples using gas chromatography coupled to mass spectrometry technique.
It is a derivatization agent in GC-MS technique used as an alternative to trifluoroacetyl anhydride (TFAA) for trifluoroacylating primary and secondary amines, and the hydroxyl group under mild non-acidic conditions.
Reagent for introducing trifluoroacetyl group. Suitable for the derivatization of alcohols, amines, amino acids, carbohydrates(mono-,di-,tri- and tetrasaccharides, carboxylic acids, hydroxyamines, 3-hydroxy-1-nitrosopyrrolidine, indolalkylamine, phenolalkylamines, pyridoxal (and other B₆ vitamers), and thiols.

Reagent for introducing trifluoroacetyl group.

기타 정보

Reagent for trifluoroacetyl, N-trimethylsilyl-N-tifluoroacetyl and trimethylsilyl.

Reagent for trifluoroacetylations under mild conditions

법적 정보

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS02,GHS05
• 신호어: Danger
• 유해 및 위험 성명서: H226,H314
• 예방조치 성명서: P210 - P233 - P240 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Flam. Liq. 3 - Skin Corr. 1B
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point (°F): 113.0 °F - closed cup
• Flash Point (°C): 45 °C - closed cup
• 개인 보호 장비: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter