Name: Tamoxifen
Brand: SIAL

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About This Item

Linear Formula:

C₆H₅C(C₂H₅)=C(C₆H₅)C₆H₄OCH₂CH₂N(CH₃)₂

CAS Number:

10540-29-1

Molecular Weight:

371.51

EC Number:

234-118-0

MDL number:

MFCD00010454

UNSPSC 코드:

41116107

PubChem Substance ID:

329769367

NACRES:

NA.24

기술 서비스

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도움 문의

Grade

analytical standard

Quality Level

100

분석

≥98.0% (HPLC)

유통기한

limited shelf life, expiry date on the label

기술

HPLC: suitable
gas chromatography (GC): suitable

불순물

≤0.5% water

mp

97-98 °C (lit.)

응용 분야

forensics and toxicology
pharmaceutical (small molecule)

형식

neat

저장 온도

2-8°C

SMILES string

CC\C(c1ccccc1)=C(/c2ccccc2)c3ccc(OCCN(C)C)cc3

InChI

1S/C26H29NO/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3/h5-18H,4,19-20H2,1-3H3/b26-25-

InChI key

NKANXQFJJICGDU-QPLCGJKRSA-N

유전자 정보

human ... ESR1(2099)

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애플리케이션

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

생화학적/생리학적 작용

Estrogen antagonist in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells. Protein kinase C inhibitor.

Protein kinase C inhibitor. Induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells.