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Merck

ESR1

estrogen receptor 1

동의어:
ER, ESR, ESRA, ESTRR, Era, NR3A1
종:
Human ESR1 (2099), Mouse Esr1 (13982), Rat Esr1 (24890), Goat ESR1 (100860768), sheep ESR1 (443228), domestic guinea pig Esr1 (100713276), Zebrafish esr1 (259252), dog ESR1 (403640), cow ESR1 (407238), Horse ESR1 (791249) ...더
UniProtKB ID:
P03372, Q13511, Q14276, Q5T5H7, Q6MZQ9, Q9NU51, Q9UDZ7, Q9UIS7
Clone ID:
  • Human(2099) Summary: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq, Jul 2008]
  • Mouse(13982) estrogen receptor 1 (alpha)
  • Rat(24890) estrogen receptor 1
  • Goat(100860768) estrogen receptor 1
  • sheep(443228) estrogen receptor 1
  • domestic guinea pig(100713276) estrogen receptor 1
  • Zebrafish(259252) estrogen receptor 1
  • dog(403640) estrogen receptor 1
  • cow(407238) estrogen receptor 1
  • Horse(791249) estrogen receptor 1
  • domestic cat(552888) estrogen receptor 1
  • chicken(396099) estrogen receptor 1
  • Thale Cress(837856) ethylene-responsive transcription factor ESR1

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Small Molecule - Activator

Product Number
설명
종
131083
4-Phenylazophenol, 98%,
종
human
262013
trans-4-Stilbenemethanol, ,
종
human, rat
S4808
cis-Stilbene, 96%,
종
human, rat
N0632
β-Nicotinamide adenine dinucleotide sodium salt, ,
종
human
N6522
β-Nicotinamide adenine dinucleotide hydrate, BioUltra, ≥98%, from yeast,
종
human

Small Molecule - Agonist

Product Number
설명
종
855871
Mestranol, 99%,
종
human
E8004
β-Estradiol 17-cypionate, ,
종
human
H6036
1,3,5-Tris(4-hydroxyphenyl)-4-propyl-1H-pyrazole, powder, ≥98% (HPLC),
종
human
E-075
Estrone solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
종
human
PHR1480
Ethinyl Estradiol, Pharmaceutical Secondary Standard; Certified Reference Material,
종
human

Small Molecule - Allosteric Modulator

Product Number
설명
종
T0015000
Tamoxifen citrate for performance test, European Pharmacopoeia (EP) Reference Standard,
종
human
85256
Tamoxifen, analytical standard,
종
human
06734
Tamoxifen, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland,
종
human
1643306
Tamoxifen citrate, United States Pharmacopeia (USP) Reference Standard,
종
human
T0014000
Tamoxifen citrate, European Pharmacopoeia (EP) Reference Standard,
종
human

Small Molecule - Antagonist

Product Number
설명
종
442858
4-tert-Octylphenol, analytical standard,
종
mouse
C33301
2-Chloro-4,6-diamino-1,3,5-triazine, 95%,
종
mouse
290823
4-tert-Octylphenol, 97%,
종
mouse
308501
Benzyl butyl phthalate, 98%,
종
mouse
524980
Dibutyl phthalate, 99%,
종
mouse

Antibodies

Product Number
설명
종별 반응성
응용분야
SAB5701845
Anti-Phospho-ESRα-S118 antibody produced in rabbit, ,
종별 반응성
human
응용분야
western blot
SAB5702607
Anti-ESRα Antibody, clone 4L8K5, Rabbit Monoclonal, ,
종별 반응성
human, rat
응용분야
immunofluorescence
western blot
SAB4300344
Anti-ESR1 (Ab-104) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
immunohistochemistry
western blot
SAB4300346
Anti-ESR1 (Ab-118) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry
western blot
SAB4300052
Anti-phospho-ESR1 (pSer104) antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
immunohistochemistry
western blot

Small Molecule - Inhibitor

Product Number
설명
종
D79403
Bicyclohexyl, 99%,
종
human
W312908
Biphenyl, ≥99%,
종
human
B34656
Biphenyl, ReagentPlus®, 99.5%,
종
human
374784
4′-Hydroxy-4-biphenylcarbonitrile, 97%,
종
human
168734
4,4′-Dihydroxybiphenyl, 97%,
종
human

Small Molecule - Ligand

Product Number
설명
종
46665
Progesterone, VETRANAL®, analytical standard,
종
human
H4637
4-Hydroxyestradiol, ,
종
rat, human
T5648
Tamoxifen, ≥99%,
종
human, rat
P0130
Progesterone, ≥99%,
종
mouse, human, rat
P3972
Progesterone, meets USP testing specifications,
종
mouse, human, rat

Small Molecule - Mixed Agonist/Antagonist

Product Number
설명
종
E8750
α-Estradiol, powder, ≥98% (TLC),
종
human, rat
M1629
Medroxyprogesterone 17-acetate, ≥97% (HPLC),
종
human, rat
E1024
Estradiol, meets USP testing specifications,
종
human, mouse, rat
E1132
β-Estradiol, analytical standard,
종
human, mouse, rat
E2257
β-Estradiol, powder, γ-irradiated, suitable for cell culture,
종
human, mouse, rat

Proteins

Product Number
설명
종
E1528
Estrogen Receptor-α human, ≥80% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
종
human

esiRNA

Product Number
설명
종
EHU141651
MISSION® esiRNA, targeting human ESR1,
종
human