90970

γ-Butyrolactone

analytical standard

• 동의어(들): γ-Hydroxybutyric acid lactone, 4-Hydroxybutyric acid lactone, GBL
• 실험식(Hill 표기법): C₄H₆O₂
• CAS Number: 96-48-0
• Molecular Weight: 86.09
• Beilstein: 105248
• EC Number: 202-509-5
• MDL number: MFCD00005386
• UNSPSC 코드: 85151701
• PubChem Substance ID: 329769980
• NACRES: NA.24

속성

• Grade: analytical standard
• Quality Level: 100
• vapor density: 3 (vs air)
• vapor pressure: 1.5 mmHg ( 20 °C)
• 분석: ≥99.0% (GC)
• autoignition temp.: 851 °F
• 유통기한: limited shelf life, expiry date on the label
• expl. lim.: 16 %
• 기술: HPLC: suitable; gas chromatography (GC): suitable
• 불순물: ≤0.3% water
• refractive index: n20/D 1.436 (lit.)
• bp: 204-205 °C (lit.)
• mp: −45 °C (lit.)
• density: 1.12 g/mL at 25 °C (lit.)
• 응용 분야: cleaning products; cosmetics; flavors and fragrances; food and beverages; personal care
• 형식: neat
• 저장 온도: 2-8°C
• SMILES string: O=C1CCCO1
• InChI: 1S/C4H6O2/c5-4-2-1-3-6-4/h1-3H2
• InChI key: YEJRWHAVMIAJKC-UHFFFAOYSA-N

설명

일반 설명

γ-Butyrolactone (GBL) is a related lactone analog of γ-hydroxybutyric acid (GHB), a widespread drug of abuse, identified as an endogenous constituent of the mammalian brain, in which it exhibits a strong central nervous system depressant effect. GBL is considered as a legal substitute of GHB, and commonly identified in beverages including coffee, apple cider vinegar, tea, carbonated drinks, etc.

애플리케이션

γ-Butyrolactone may be used as an analytical reference standard for the quantification of the analyte in roasted Italian chestnuts, wine samples, beverages using chromatography techniques.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

생화학적/생리학적 작용

Precursor of γ-hydroxybutyric acid (GHB). It blocks dopamine release by blocking impulse flow in dopaminergic neurons. Pretreatment with γ-butyrolactone allows detection of autoreceptor-induced dopamine release.

Precursor of γ-hydroxybutyric acid (GHB); blocks dopamine release.

안전성 정보

• 픽토그램: GHS05,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H302,H318,H336
• 예방조치 성명서: P261 - P264 - P271 - P280 - P301 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - STOT SE 3
• 표적 기관: Central nervous system
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): 208.4 °F - closed cup
• Flash Point (°C): 98 °C - closed cup