C1484
7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin
≥95% purity (HPLC), solid
동의어(들):
1H-Pyrrole-2,5-dione, 1-(4-(7-(diethylamino)-4-methyl-2-oxo-2H-1-benzopyran-3-yl)phenyl)-, CPM
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C24H22N2O4
CAS Number:
Molecular Weight:
402.44
MDL number:
UNSPSC 코드:
12171500
PubChem Substance ID:
NACRES:
NA.47
추천 제품
Product Name
7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin, ≥95% (HPLC), solid
Quality Level
분석
≥95% (HPLC)
양식
solid
기술
titration: suitable
색상
yellow
solubility
DMSO: soluble
methanol: soluble
응용 분야
diagnostic assay manufacturing
hematology
histology
저장 온도
−20°C
SMILES string
CCN(CC)c1ccc2C(C)=C(C(=O)Oc2c1)c3ccc(cc3)N4C(=O)C=CC4=O
InChI
1S/C24H22N2O4/c1-4-25(5-2)18-10-11-19-15(3)23(24(29)30-20(19)14-18)16-6-8-17(9-7-16)26-21(27)12-13-22(26)28/h6-14H,4-5H2,1-3H3
InChI key
YGIABALXNBVHBX-UHFFFAOYSA-N
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일반 설명
7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin (CPM), is a highly fluorescent, sulfhydryl (-SH) group containing coumarin derivative. It has excitation an emission wavelengths of 355 and 460 nm, respectively.
애플리케이션
7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin has been used:
- as a nontoxic substitute for conjugation with antibody(93)
- to aid fluorescent detection of Coenzyme A (CoA-SH) in human N-myristoyltransferases assay (94)
- in thermostability shift assay of recombinant protein(95)
생화학적/생리학적 작용
Used to monitor release of thiols, quantitate thiol in microplate reactions, and to distinguish proliferating cancer cells by nucleolar protein staining.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
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