E1271

N-Ethylmaleimide

BioXtra, ≥98% (HPLC)

• 동의어(들): NEM
• 실험식(Hill 표기법): C₆H₇NO₂
• CAS Number: 128-53-0
• Molecular Weight: 125.13
• Beilstein: 112448
• EC Number: 204-892-4
• MDL number: MFCD00005509
• UNSPSC 코드: 12352106
• PubChem Substance ID: 24894398
• NACRES: NA.21

속성

• 제품 라인: BioXtra
• Quality Level: 200
• 분석: ≥98% (HPLC)
• 불순물: ≤0.001% Phosphorus (P); ≤0.1% Insoluble matter
• 무기 잔류물: ≤0.1%
• bp: 210 °C (lit.)
• mp: 43-46 °C (lit.)
• solubility: 95% ethanol: 50 mg/mL, clear to slightly hazy (colorless to faint yellow)
• 음이온 미량물: chloride (Cl^-): ≤0.05%; sulfate (SO₄^2-): ≤0.05%
• 양이온 미량물: Al: ≤0.0005%; Ca: ≤0.0005%; Cu: ≤0.0005%; Fe: ≤0.0005%; K: ≤0.005%; Mg: ≤0.0005%; Na: ≤0.005%; Pb: ≤0.001%; Zn: ≤0.0005%
• 저장 온도: 2-8°C
• SMILES string: CCN1C(=O)C=CC1=O
• InChI: 1S/C6H7NO2/c1-2-7-5(8)3-4-6(7)9/h3-4H,2H2,1H3
• InChI key: HDFGOPSGAURCEO-UHFFFAOYSA-N
• 유전자 정보: human ... SLC6A3(6531), SLC6A4(6532)

설명

애플리케이션

Reagent for the covalent modification of cysteine residues in proteins.

생화학적/생리학적 작용

Augments currents from native M-channels in sympathetic neurons and acts as an opener for KCNQ2, KCNQ4 and KCNQ5 channels.

Sulfhydryl alkylating agent that inactivates NADP-dependent isocitrate dehydrogenase and many endonucleases.

안전성 정보

• 픽토그램: GHS06,GHS05
• 신호어: Danger
• 유해 및 위험 성명서: H300,H311,H314,H317
• 예방조치 성명서: P260 - P272 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point (°F): 163.2 °F - closed cup
• Flash Point (°C): 72.9 °C - closed cup
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges