SMB00947

N-Desethyl amodiaquine dihydrochloride

≥95%

• 동의어(들): Monodesethylamodiaquine dihydrochloride
• 실험식(Hill 표기법): C₁₈H₁₈ClN₃O · 2HCl
• CAS Number: 79049-30-2
• Molecular Weight: 400.73
• UNSPSC 코드: 41116107
• NACRES: NA.77

속성

• 생물학적 소스: synthetic
• Quality Level: 200
• 분석: ≥95%
• 양식: solid
• 분자량: 400.73 g/mol
• 기술: HPLC: suitable
• 색상: yellow to dark yellow
• solubility: DMSO: soluble; methanol: soluble; water: soluble
• 저장 온도: 2-8°C

설명

애플리케이션

Amodiaquine (AQ) is currently used in combination with Artesunate (AS) as first-line treatment for some cases of falciparum malaria (UM) in many countries. AQ is metabolized by hepatic cytochrome P450 2C8 (CYP2C8) to Desethylamodiaquine (DAQ; DEAQ; NADQ; Ndes-amo), which is subsequently eliminated via extra-hepatic biotransformation by CYP1A1 and CYP1B1. DEAQ is responsible for the pharmacological activity of AQ (both therapeutic and toxicity) due to its long elimination half-life.

Metabolomics research

기타 정보

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안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable