12247

Oleuropein

≥98.0%

• 동의어(들): (2S,3E,4S)-3-Ethylidene-2-(β-D-glucopyranosyloxy)-3,4-dihydro-5-(methoxycarbonyl)-2H-pyran-4-acetic acid 2-(3,4-dihydroxyphenyl)ethyl ester
• 실험식(Hill 표기법): C₂₅H₃₂O₁₃
• CAS Number: 32619-42-4
• Molecular Weight: 540.51
• EC Number: 251-129-6
• MDL number: MFCD16879008
• UNSPSC 코드: 12352202
• PubChem Substance ID: 329749662
• NACRES: NA.32

속성

• Quality Level: 100
• 분석: ≥98.0%
• 불순물: ≤5.0% water
• 응용 분야: metabolomics; vitamins, nutraceuticals, and natural products
• SMILES string: COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)\C(=C\C)[C@@H]1CC(=O)OCCc3ccc(O)c(O)c3
• InChI: 1S/C25H32O13/c1-3-13-14(9-19(29)35-7-6-12-4-5-16(27)17(28)8-12)15(23(33)34-2)11-36-24(13)38-25-22(32)21(31)20(30)18(10-26)37-25/h3-5,8,11,14,18,20-22,24-28,30-32H,6-7,9-10H2,1-2H3/b13-3+/t14-,18+,20+,21-,22+,24-,25-/m0/s1
• InChI key: RFWGABANNQMHMZ-ZCHJGGQASA-N

설명

일반 설명

Oleuropein is the major secondary metabolite found in the olive leaf extract. It is a secoiridoid polyphenol with a structure comprising of a glycosylated ester of elenolic acid with hydroxytyrosol.

애플리케이션

Oleuropein has been used:

• as an anti-inflammatory and antioxidant agent in hepatic steatosis on high-fat diet (HFD) fed mice
• to evaluate protective effects and antioxidant properties on male reproductive function in mice
• to study its inhibitory effects on bacterial (E. coli) ATP synthase
• as an inhibitor of plasminogen activator inhibitor-1 (PAI-1) to test its effect on the proliferation of breast cancer cells

생화학적/생리학적 작용

Oleuropein has anti-cancer, antimicrobial, antiviral, anti-ischemic and hypolipidemic activities. It functions as a skin protectant and aids anti-aging. Oleuropein is also implicated in anti-platelet aggregation, hypotensive, anti-rheumatic, antipyretic, diuretic and vasodilatory effects. It reduces the risk of coronary artery diseases. Oleuropein has been shown to augment the secretion of noradrenaline and adrenaline in rat.

포장

Bottomless glass bottle. Contents are inside inserted fused cone.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable