40674

Pinoresinol

≥95.0% (HPLC)

• 동의어(들): (+)-Pinoresinol, 4,4′-((1S,3aR,4S,6aR)-Hexahydrofuro[3,4-c]furan-1,4-diyl)bis(2-methoxyphenol), 4,4′-[(1S,3aR,4S,6aR)-Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis(2-methoxyphenol)
• 실험식(Hill 표기법): C₂₀H₂₂O₆
• CAS Number: 487-36-5
• Molecular Weight: 358.39
• MDL number: MFCD07784516
• UNSPSC 코드: 12352205
• PubChem Substance ID: 329756010
• NACRES: NA.25

속성

• Quality Level: 100
• 분석: ≥95.0% (HPLC)
• 양식: powder or crystals
• 응용 분야: metabolomics; vitamins, nutraceuticals, and natural products
• SMILES string: COc1cc(ccc1O)[C@H]2OC[C@H]3[C@@H]2CO[C@@H]3c4ccc(O)c(OC)c4
• InChI: 1S/C20H22O6/c1-23-17-7-11(3-5-15(17)21)19-13-9-26-20(14(13)10-25-19)12-4-6-16(22)18(8-12)24-2/h3-8,13-14,19-22H,9-10H2,1-2H3/t13-,14-,19+,20+/m0/s1
• InChI key: HGXBRUKMWQGOIE-AFHBHXEDSA-N

설명

일반 설명

Pinoresinol is a secondary metabolite, a lignan found in wide varieties of plants. Structurally, it is one of the simple lignans, with a dimer of coniferyl alcohol, which forms the bicyclic ring core.

애플리케이션

Pinoresinol has been used:

• as a reference standard for qualitative and quantitative analysis of lignans from Triticale (X Triticosecale Wittmack) grains using ultra-performance liquid chromatography (UPLC) with photodiode and mass TQD detectors
• as an enterolignan precursor to study its estrogenic activity on the proliferation of human breast cancer MCF-7 cells
• as a reference standard for lignan analysis of Sesamum indicum L. seeds

생화학적/생리학적 작용

Pinoresinol is present in a number of plants including medical plants like Sambucus williamsii, Eucommia ulmoides (duzhong), Styrax sp, Forsythia suspensa, and in extra virgin olive oil. The genus Sambucus is widely distributed in Europe, Asia, and North Africa, and has been used in traditional medicine as an analgesic, antivirus, antiinflammatory, homoeostatic, and diuretic drugs which act on bruises, fractures, and edema. Pinoresinol displays potent antifungal properties by causing damage to the fungal plasma membrane. It exerts anti-oxidative and anti-inflammatory activities by inhibition of TNF- α production (presumably through inhibition of NF- κB and AP-1).

exerts anti-oxidative and anti-inflammatory activities by inhibition of TNF-α production

포장

Bottomless glass bottle. Contents are inside inserted fused cone.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable