46955

Fluorescein

free acid

• 동의어(들): Acid Yellow 73
• 실험식(Hill 표기법): C₂₀H₁₂O₅
• CAS Number: 2321-07-5
• Molecular Weight: 332.31
• 색상 지수 번호: 45350
• Beilstein: 94324
• EC Number: 219-031-8
• MDL number: MFCD00005050
• UNSPSC 코드: 12171500
• PubChem Substance ID: 329757275
• NACRES: NA.32

속성

• Quality Level: 100
• 기술: titration: suitable
• 형광: λ_ex 490 nm; λ_em 514 nm in 0.1 M Tris pH 8.0
• 적합성: suitable for fluorescence
• SMILES string: Oc1ccc2c(Oc3cc(O)ccc3C24OC(=O)c5ccccc45)c1
• InChI: 1S/C20H12O5/c21-11-5-7-15-17(9-11)24-18-10-12(22)6-8-16(18)20(15)14-4-2-1-3-13(14)19(23)25-20/h1-10,21-22H
• InChI key: GNBHRKFJIUUOQI-UHFFFAOYSA-N
• 유전자 정보: human ... PTPN1(5770), PTPRF(5792)

설명

일반 설명

Fluorescein dye is the most commonly used fluorescent probe. It is used to stain epithelial defects and analyse the integrity of corneal epithelium. Fluorescein is used in the diagnosis of corneal perforation. Oral or intravenous fluorescein is used in fluorescein angiography to detect diabetic retinopathy and choroidal neovascular membrane.

애플리케이션

Fluorescein has been used:

• in the permeability assay of Caco-2 cells
• to test its suitability to serve as lifetime fluorescence standards
• as a fluorophore for the fast recovery of fluorescence peaks and fluorophore concentration in the presence of hemoglobin
• as a fluorescent probe in oxygen radical absorbance capacity (ORAC) assay

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H319
• 예방조치 성명서: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)