80635

PIPES

BioXtra, Molecular Biology, ≥99.5% (T)

• 동의어(들): 1,4-Piperazinediethanesulfonic acid, Piperazine-1,4-bis(2-ethanesulfonic acid), Piperazine-N,N′-bis(2-ethanesulfonic acid)
• 실험식(Hill 표기법): C₈H₁₈N₂O₆S₂
• CAS Number: 5625-37-6
• Molecular Weight: 302.37
• Beilstein: 817713
• EC Number: 227-057-6
• MDL number: MFCD00006159
• UNSPSC 코드: 12161700
• PubChem Substance ID: 57652837
• NACRES: NA.25

속성

• Grade: Molecular Biology
• Quality Level: 100
• 제품 라인: BioXtra
• 분석: ≥99.5% (T)
• 양식: powder
• 불순물: DNases, none detected; RNases, none detected; insoluble matter, passes filter test; phosphatases, none detected; proteases, none detected
• 무기 잔류물: ≤0.2% (as SO₄)
• 손실: ≤0.2% loss on drying, 110 °C
• 유용한 pH 범위: 6.1-7.5
• pKa(25 °C): 6.8
• mp: >300 °C (lit.)
• solubility: 0.1 M NaOH: 0.1 M at 20 °C, clear, colorless
• 음이온 미량물: chloride (Cl^-): ≤200 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg
• 양이온 미량물: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; Na: ≤100 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• λ: 0.1 M in 1 M NaOH
• UV 흡수: λ: 260 nm A_max: 0.055; λ: 280 nm A_max: 0.040
• SMILES string: OS(=O)(=O)CCN1CCN(CC1)CCS(O)(=O)=O
• InChI: 1S/C8H18N2O6S2/c11-17(12,13)7-5-9-1-2-10(4-3-9)6-8-18(14,15)16/h1-8H2,(H,11,12,13)(H,14,15,16)
• InChI key: IHPYMWDTONKSCO-UHFFFAOYSA-N

설명

애플리케이션

• Sensitive Detection of Immunoglobulin G Stability Using in Real-Time Isothermal Differential Scanning Fluorimetry: Determinants of Protein Stability for Antibody-Based Therapeutics.: The use of PIPES buffer in this study was integral to maintaining the stability of immunoglobulin G during differential scanning fluorimetry. This method is crucial for evaluating the stability of antibody-based therapeutics (Moggridge et al., 2017).

기타 정보

Hybrid selection of mRNA - component of prehybridization buffer.

안전성 정보

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)