A2056

Acetyl coenzyme A trisodium salt

≥93% (HPLC), powder

• 동의어(들): Acetyl-S- CoA, Acetyl CoA
• 실험식(Hill 표기법): C₂₃H₃₅N₇O₁₇P₃S · 3Na
• CAS Number: 102029-73-2
• Molecular Weight: 875.52
• MDL number: MFCD00078858
• UNSPSC 코드: 41106305
• PubChem Substance ID: 24890621
• NACRES: NA.51

속성

• Quality Level: 300
• 분석: ≥93% (HPLC)
• 양식: powder
• solubility: H₂O: 100 mg/mL
• 저장 온도: −20°C
• SMILES string: O[C@H]1[C@](O[C@@H]([C@H]1OP(O)(O)=O)COP(OP(OCC(C)(C)[C@@H](O)C(NCCC(NCCSC(C)=O)=O)=O)(O)=O)(O)=O)([H])N2C3=NC=NC(N)=C3N=C2.[3Na]
• InChI: 1S/C23H38N7O17P3S.Na/c1-12(31)51-7-6-25-14(32)4-5-26-21(35)18(34)23(2,3)9-44-50(41,42)47-49(39,40)43-8-13-17(46-48(36,37)38)16(33)22(45-13)30-11-29-15-19(24)27-10-28-20(15)30;/h10-11,13,16-18,22,33-34H,4-9H2,1-3H3,(H,25,32)(H,26,35)(H,39,40)(H,41,42)(H2,24,27,28)(H2,36,37,38);/q;+1/p-1/t13-,16-,17-,18?,22-;/m1./s1
• InChI key: HNLIOWFIXSPFEC-WLYMNMRISA-M
• 유전자 정보: human ... CHAT(1103), HAT1(8520), KAT2A(2648), KAT2B(8850), KAT5(10524) ; mouse ... HAT1(107435), KAT2A(14534), KAT2B(18519), KAT5(81601) ; rat ... HAT1(296501), KAT2A(303539), KAT2B(301164), KAT5(192218)

설명

애플리케이션

Acetyl-CoA is an essential cofactor and carrier of acyl groups in enzymatic acetyl transfer reactions. Acetyl CoA is formed either by the oxidative decarboxylation of pyruvate in mitochondria, by the oxidation of long-chain fatty acids, or by the oxidative degradation of certain amino acids. Acetyl-CoA is the starting compound for the citric acid cycle (Krebs cycle). Acetyl CoA is also a key precursor in lipid biosynthesis, and the source of all fatty acid carbons. Acetyl-CoA positively regulates the activity pyruvate carboxylase. Acetyl CoA is a precursor of the neurotransmitter acetylcholine. Histone acetylases (HAT) use Acetyl-CoA as the donor for the acetyl group use in the post-translational acetylation reactions of histone and non-histone proteins.

An essential cofactor in enzymatic acetyl transfer reactions.

생화학적/생리학적 작용

Acetyl-CoA is an essential cofactor and carrier of acyl groups in enzymatic acetyl transfer reactions.

Acetyl-CoA is an essential cofactor and carrier of acyl groups in enzymatic acetyl transfer reactions. It is formed either by the oxidative decarboxylation of pyruvate in mitochondria, by the oxidation of long-chain fatty acids, or by the oxidative degradation of certain amino acids. Acetyl-CoA is the starting compound for the citric acid cycle (Kreb′s cycle). It is also a key precursor in lipid biosynthesis, and the source of all fatty acid carbons. Acetyl-CoA positively regulates the activity pyruvate carboxylase. It is a precursor of the neurotransmitter acetylcholine. Histone acetylases (HAT) use Acetyl-CoA as the donor for the acetyl group use in the post-translational acetylation reactions of histone and non-histone proteins.

제조 메모

Prepared enzymatically

기타 정보

For more more technical information and a complete list of Coenzyme A deriviatives visit the Acyl Transfer Reagents Resource.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type N95 (US)