Name: Adenine
Brand: SIGMA

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About This Item

실험식(Hill 표기법):

C₅H₅N₅

CAS Number:

73-24-5

Molecular Weight:

135.13

Beilstein:

5777

EC Number:

200-796-1

MDL number:

MFCD00041790

UNSPSC 코드:

12352205

PubChem Substance ID:

24890691

NACRES:

NA.75

기술 서비스

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도움 문의

생물학적 소스

synthetic

제품 라인

BioReagent

분석

≥99%

양식

powder

분자량

M_w 135.13 g/mol

기술

cell culture | mammalian: suitable

색상

white to off-white

mp

>360 °C (lit.)

solubility

0.5 M HCl: soluble 20 mg/mL, clear to slightly hazy, colorless to faintly yellow

저장 온도

room temp

SMILES string

Nc1ncnc2[nH]cnc12

InChI

1S/C5H5N5/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H3,6,7,8,9,10)

InChI key

GFFGJBXGBJISGV-UHFFFAOYSA-N

유전자 정보

human ... AKT1(207), GSK3B(2932), LCK(3932), MAP3K1(4214), MAPK14(1432), MAPK8(5599), MAPK9(5601), MAPKAPK2(9261), PRKACA(5566), PRKCA(5578), RAF1(5894), ROCK2(9475)
mouse ... Mapk1(26413)
rat ... Camk2a(25400), Mapk10(25272)

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일반 설명

Adenine is a purine nucleobase, synthesized from inosine monophosphate(IMP). It is a nitrogenous heterocyclic aromatic compound.

애플리케이션

Adenine has been used:

a component of green medium used for the derivation of keratinocytes from plucked hair follicles
for the serial culture of adult murine keratinocytes
as a media component for SSEA4⁺ limbal stromal stem cell differentiation

생화학적/생리학적 작용

Adenine is a component of important biomolecules such as adenosine triphosphate (ATP), nicotinamide adenine dinucleotide (NAD) and flavin adenine dinucleotide (FAD). NAD and FAD forms the structure of DNA and RNA, and plays important role in protein synthesis. ATP is an energy source, that is essential for cellular respiration.