A5922

Amifostine trihydrate

≥97% (TLC), powder

• 동의어(들): 2-(3-Aminopropyl)aminoethyl phosphorothioate, WR2721
• 실험식(Hill 표기법): C₅H₁₅N₂O₃PS · 3 H₂O
• CAS Number: 112901-68-5
• Molecular Weight: 268.27
• MDL number: MFCD00453866
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24278231
• NACRES: NA.77

속성

• Quality Level: 200
• 분석: ≥97% (TLC)
• 양식: powder
• 저장 온도: 2-8°C
• SMILES string: OP(SCCNCCCN)(O)=O.O.O.O
• InChI: 1S/C5H15N2O3PS.3H2O/c6-2-1-3-7-4-5-12-11(8,9)10;;;/h7H,1-6H2,(H2,8,9,10);3*1H2
• InChI key: TXQPXJKRNHJWAX-UHFFFAOYSA-N

설명

애플리케이션

Amifostine may provide renal protection during PRRT using somatostatin analogs by mitigating radiation damage and reducing the absorbed kidney radiation dose. Amifostine remediates the degenerative effects of radiation on the mineralization capacity of the murine mandible.

생화학적/생리학적 작용

Radioprotective agent. Selectively protects normal tissues from the damaging effects of anti-neoplastic radiation therapy. Selectivity is due to preferential uptake by normal tissues and subsequent metabolic activation to 2-(3-aminopropyl)aminoethanethiol.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• 예방조치 성명서: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves