A6671
Actinonin
≥98% (TLC), powder, leucine aminopeptidase inhibitor
동의어(들):
3-[[1-[(2-(Hydroxymethyl)-1-pyrrolidinyl)carbonyl]-2-methylpropyl]carbamoyl]octanohydroxamic acid
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모든 사진(2)
About This Item
실험식(Hill 표기법):
C19H35N3O5
CAS Number:
Molecular Weight:
385.50
Beilstein:
1555250
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.77
추천 제품
Product Name
Actinonin,
생물학적 소스
synthetic (organic)
Quality Level
분석
≥98% (TLC)
양식
powder
solubility
ethanol: 50 mg/mL, clear, colorless
항생제 활성 스펙트럼
Gram-negative bacteria
Gram-positive bacteria
동작 모드
enzyme | inhibits
저장 온도
−20°C
SMILES string
CCCCCC(CC(=O)NO)C(=O)NC(C(C)C)C(=O)N1CCCC1CO
InChI
1S/C19H35N3O5/c1-4-5-6-8-14(11-16(24)21-27)18(25)20-17(13(2)3)19(26)22-10-7-9-15(22)12-23/h13-15,17,23,27H,4-12H2,1-3H3,(H,20,25)(H,21,24)
InChI key
XJLATMLVMSFZBN-UHFFFAOYSA-N
유전자 정보
human ... ANPEP(290), DPP4(1803), ECE1(1889), LAP3(51056)
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관련 카테고리
일반 설명
Chemical structure: peptide
애플리케이션
Actinonin has been used as a control to inhibit meprin-β activity in C57BL/6 mice. It has also been used to study the high-affinity interaction of EcPDF with actinonin by 15N NMR spectroscopy and isothermal titration.
생화학적/생리학적 작용
Actinonin has inhibitory action against peptide deformylase (PDF). It is effective against Gram-positive and fastidious Gram-negative microorganisms.
Actinonin is an inhibitor of leucine aminopeptidase. Actinonin has also been used to improve antibacterial activity and antiobesity therapeutics.
특징 및 장점
This compound is featured on the Neuropeptidases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
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시험 성적서(COA)
Lot/Batch Number
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