A6816

(±)-AMPA

solid

• 동의어(들): (±)-α-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid hydrate
• 실험식(Hill 표기법): C₇H₁₀N₂O₄
• Molecular Weight: 186.17
• MDL number: MFCD00213388
• UNSPSC 코드: 12352100
• PubChem Substance ID: 24891141
• NACRES: NA.32

속성

• 양식: solid
• 색상: white
• solubility: H₂O: 1 mg/mL (warm); 0.1 M HCl: 3.5 mg/mL; 0.1 M NaOH: 4.3 mg/mL; DMSO: 4.3 mg/mL; 1 M HCl: 50 mg/mL
• SMILES string: O.Cc1onc(O)c1CC(N)C(O)=O
• InChI: 1S/C7H10N2O4.H2O/c1-3-4(6(10)9-13-3)2-5(8)7(11)12;/h5H,2,8H2,1H3,(H,9,10)(H,11,12);1H2
• InChI key: HFISYNCCKQHIAM-UHFFFAOYSA-N
• 유전자 정보: rat ... Gria1(50592), Gria2(29627), Gria3(29628), Gria4(29629), Grik1(29559), Grik2(54257), Grin2a(24409), Grm1(24414), Grm2(24415), Grm4(24417), Grm5(24418), Slc1a1(25550), Slc1a2(29482), Slc1a3(29483)

설명

애플리케이션

(±)-AMPA has been used:

• in vivo

• whole-cell patch-clamp recording in Müller glial cells
• to test its excitotoxic effects in hippocampal slice cultures
• in retinal horizontal cells (HCs) culture to test its effect on Ca²⁺ signals

생화학적/생리학적 작용

Potent excitatory amino acid that interacts selectively with central AMPA/kainate receptors.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)