A7611

Azelastine hydrochloride

≥98% (HPLC)

• 동의어(들): 4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)phthalazin-1-one hydrochloride, Astelin, Optivar
• 실험식(Hill 표기법): C₂₂H₂₄ClN₃O · HCl
• CAS Number: 79307-93-0
• Molecular Weight: 418.36
• MDL number: MFCD00242783
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329770938
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 저장 조건: desiccated
• 색상: white to off-white
• solubility: DMSO: >10 mg/mL
• 주관자: Wallace
• 저장 온도: −20°C
• SMILES string: Cl.CN1CCCC(CC1)N2N=C(Cc3ccc(Cl)cc3)c4ccccc4C2=O
• InChI: 1S/C22H24ClN3O.ClH/c1-25-13-4-5-18(12-14-25)26-22(27)20-7-3-2-6-19(20)21(24-26)15-16-8-10-17(23)11-9-16;/h2-3,6-11,18H,4-5,12-15H2,1H3;1H
• InChI key: YEJAJYAHJQIWNU-UHFFFAOYSA-N
• 유전자 정보: human ... HRH1(3269)

설명

애플리케이션

Azelastine hydrochloride is a H1 histamine receptor antagonist and NF-kB activator. Azelastine hydrochloride has been used in a study to investigate the potential of polymeric microspheres for treatment of allergic conjunctivitis.

생화학적/생리학적 작용

H1 histamine receptor antagonist; NF-kB activator.

특징 및 장점

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Wallace. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• 예방조치 성명서: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable